Liver Function

You can train your body into thinking it's had medicine

Marette Flies was 11 when her immune system turned against her. A cheerful student from Minneapolis, Minnesota, she had curly brown hair and a pale, moon-shaped face, and she loved playing trumpet in her high-school band. ...

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Uncovering cardiovascular disease genetics

February is American Heart Month, a great time to take a closer look at cardiovascular disease (CVD). According to the World Health Organization (WHO), about 17.5 million people die each year from CVD, a figure representing ...

Feb 08, 2016
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Microreactor replaces animal testing

Researchers all over Europe are working on alternatives to animal testing that can be used to evaluate the adverse side-effects of medications. But many of these test methods still present problems. A microreactor developed ...

Feb 02, 2016
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Why the calorie is broken

Calories consumed minus calories burned: it's the simple formula for weight loss or gain. But dieters often find that it doesn't work. Cynthia Graber and Nicola Twilley of Gastropod investigate.

Jan 27, 2016
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Delivering genes across the blood-brain barrier

Caltech biologists have modified a harmless virus in such a way that it can successfully enter the adult mouse brain through the bloodstream and deliver genes to cells of the nervous system. The virus could help researchers ...

Feb 01, 2016
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Study unravels link between surgery, diabetes remission

Researchers and doctors have known for years that patients who receive bariatric surgeries – gut surgeries with the goal of weight loss – often experience remission of type 2 diabetes. Clinicians find that diabetes remission ...

Jan 21, 2016
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Liver function tests (LFTs or LFs), are groups of clinical biochemistry laboratory blood assays designed to give information about the state of a patient's liver. The parameters measured include PT/INR, aPTT, albumin, billirubin (direct and indirect) and others. According to some, liver transaminases (AST/ALT (SGOT/SGPT) are not liver function tests, but are biomarkers of liver injury in a patient with some degree of intact liver function.[citation needed] Other sources include transaminases. Most liver diseases cause only mild symptoms initially, but it is vital that these diseases be detected early. Hepatic (liver) involvement in some diseases can be of crucial importance. This testing is performed by a medical technologist on a patient's serum or plasma sample obtained by phlebotomy. Some tests are associated with functionality (e.g., albumin); some with cellular integrity (e.g., transaminase) and some with conditions linked to the biliary tract (gamma-glutamyl transferase and alkaline phosphatase). Several biochemical tests are useful in the evaluation and management of patients with hepatic dysfunction. These tests can be used to (1) detect the presence of liver disease, (2) distinguish among different types of liver disorders, (3) gauge the extent of known liver damage, and (4) follow the response to treatment. Some or all of these measurements are also carried out (usually about twice a year for routine cases) on those individuals taking certain medications- anticonvulsants are a notable example- in order to ensure that the medications are not damaging the person's liver.

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