Diseases, Conditions, Syndromes

Virus might be behind mystery child hepatitis cases: US agency

Nine young children from Alabama affected by a mysterious hepatitis (inflammation of the liver) all tested positive for a common pathogen called adenovirus 41, a study by the US health agency said Friday.

Medical research

Japan newborn gets liver stem cells in world first

Doctors in Japan have successfully transplanted liver cells derived from embryonic stem cells into a newborn baby, in a world first that could provide new treatment options for infants.

Genetics

CRISPR 'minigene' approach stops genetic liver disease in mice

A new CRISPR gene-editing technique prevented a genetic liver disease known to be driven by hundreds of different mutations and improved clinical symptoms in mice, Penn Medicine researchers reported in new proof-of-concept ...

Diseases, Conditions, Syndromes

Sox9 reshapes the biliary tree in Alagille syndrome

Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues. One major characteristic of this condition is abnormalities in the ducts that carry ...

Genetics

New clues to treat Alagille syndrome from zebrafish

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies potential new therapeutic avenues for patients with Alagille syndrome. The discovery, published in Nature Communications, ...

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