Patients with the most common type of lung cancer are notoriously insensitive to chemotherapy drugs, including cisplatin. New findings related to the cellular pathways that regulate responses to cisplatin have now been published ...
Cancer Jul 26, 2012 | not rated yet | 0
Arsenic is a natural element in the environment, sometimes found in air, soil and water. Arsenic contaminated water is a global threat, currently affecting more than 100 million people. Both genetic and epigenetic changes ...
Cancer Jul 25, 2012 | not rated yet | 0
In addition to the well-known risk factor of smoking, chronic obstructive pulmonary disease (COPD) increases lung cancer risk.
Cancer Jul 24, 2012 | 5 / 5 (2) | 0
Cellular change thought to happen only in late-stage cancers to help tumors spread also occurs in early-stage lung cancer as a way to bypass growth controls, say researchers at Mayo Clinic in Florida. The finding, reported ...
Cancer Jul 11, 2012 | not rated yet | 0 |
A new research report published online in the FASEB Journal reveals a connection among sugar, cancer, and dependence on breathing machines--microRNA-320a. In the report, Stanford scientists show that the molecule microRNA-320a is res ...
Cancer Jul 06, 2012 | not rated yet | 0 |
People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will returnit's a question ...
Genetics Jul 02, 2012 | 5 / 5 (5) | 0 |
Many lung cancers are driven by mutations in the epidermal growth-factor receptor (EGFR), and so it makes sense that many successful modern treatments block EGFR activity. Unfortunately, cancers inevitably evolve around EGFR ...
Cancer Jun 29, 2012 | 5 / 5 (3) | 0 |
A new study comparing lung cancer death rates among women by year of birth shows dramatic differences in trends between states, likely reflecting the success or failure of tobacco control efforts. The study, published in ...
Cancer Jun 25, 2012 | not rated yet | 0
A lung screening and surveillance task force, established by the American Association for Thoracic Surgery (AATS) and led by medical professionals from Brigham and Women's Hospital (BWH), is strongly recommending new guidelines ...
Surgery Jun 21, 2012 | not rated yet | 0
Cancer smells different. Past research has shown that dogs can detect lung cancer in a persons breath with great accuracy. But dogs are tricky to use as a diagnostic tool; what does it mean when a dog barks once ...
Cancer Jun 19, 2012 | not rated yet | 0
A multi-institutional research study has uncovered a new mechanism that may lead to unique treatments for lung cancer, one of the leading causes of death worldwide.
Genetics Jun 18, 2012 | 5 / 5 (1) | 0 |
(HealthDay) -- A woman with early-stage lung cancer died recently after highly targeted radiation therapy zapped not just her tumor, but surrounding tissue, fatally damaging her airway.
Cancer Jun 13, 2012 | not rated yet | 0
A new compound that targets anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer is well-tolerated by patients and is already showing early signs of activity, including in patients who no longer respond to ...
Cancer Jun 01, 2012 | not rated yet | 0 |
A team of researchers led by Dr. Goutham Narla at Case Western Reserve University School of Medicine in collaboration with scientists at Mount Sinai School of Medicine in New York, have discovered a previously unrecognized ...
Cancer Jun 01, 2012 | 5 / 5 (1) | 0
A novel compound has become the first targeted therapy to benefit patients with the most common genetic subtype of lung cancer, an international clinical trial led by scientists at Dana-Farber Cancer Institute and other institutions ...
Cancer May 31, 2012 | 5 / 5 (1) | 0
Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung. If left untreated, this growth can spread beyond the lung in a process called metastasis into nearby tissue and, eventually, into other parts of the body. Most cancers that start in lung, known as primary lung cancers, are carcinomas that derive from epithelial cells. Worldwide, lung cancer is the most common cause of cancer-related death in men and women, and is responsible for 1.3 million deaths annually, as of 2004. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.
The main types of lung cancer are small-cell lung cancer (SCLC), also called oat cell cancer, and non-small-cell lung cancer (NSCLC). The most common cause of lung cancer is long-term exposure to tobacco smoke. Nonsmokers account for 15% of lung cancer cases, and these cases are often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution including secondhand smoke.
Lung cancer may be seen on chest radiograph and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. This is usually performed by bronchoscopy or CT-guided biopsy. Treatment and prognosis depend on the histological type of cancer, the stage (degree of spread), and the patient's general wellbeing, measured by performance status. Common treatments include surgery, chemotherapy, and radiotherapy. NSCLC is sometimes treated with surgery, whereas SCLC usually responds better to chemotherapy and radiation therapy. This is partly because SCLC often spreads quite early, and these treatments are generally better at getting to cancer cells that have spread to other parts of the body.
Survival depends on stage, overall health, and other factors, but overall 14% of people in the United States diagnosed with lung cancer survive five years after the diagnosis.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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