Lung Cancer

New class of RNA tumor suppressors identified

A pair of RNA molecules originally thought to be no more than cellular housekeepers are deleted in over a quarter of common human cancers, according to researchers at the Stanford University School of Medicine. Breast cancer ...

Nov 23, 2015
popularity99 comments 0

Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung. If left untreated, this growth can spread beyond the lung in a process called metastasis into nearby tissue and, eventually, into other parts of the body. Most cancers that start in lung, known as primary lung cancers, are carcinomas that derive from epithelial cells. Worldwide, lung cancer is the most common cause of cancer-related death in men and women, and is responsible for 1.3 million deaths annually, as of 2004. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.

The main types of lung cancer are small-cell lung cancer (SCLC), also called oat cell cancer, and non-small-cell lung cancer (NSCLC). The most common cause of lung cancer is long-term exposure to tobacco smoke. Nonsmokers account for 15% of lung cancer cases, and these cases are often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution including secondhand smoke.

Lung cancer may be seen on chest radiograph and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. This is usually performed by bronchoscopy or CT-guided biopsy. Treatment and prognosis depend on the histological type of cancer, the stage (degree of spread), and the patient's general wellbeing, measured by performance status. Common treatments include surgery, chemotherapy, and radiotherapy. NSCLC is sometimes treated with surgery, whereas SCLC usually responds better to chemotherapy and radiation therapy. This is partly because SCLC often spreads quite early, and these treatments are generally better at getting to cancer cells that have spread to other parts of the body.

Survival depends on stage, overall health, and other factors, but overall 14% of people in the United States diagnosed with lung cancer survive five years after the diagnosis.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Genes for a longer, healthier life found

Out of a 'haystack' of 40,000 genes from three different organisms, scientists at ETH Zurich and a research consortium in Jena have found genes that are involved in physical ageing. If you influence only one of these genes, ...

Watching eyes prevent littering

People are less likely to drop litter if it has printed eyes on it, researchers at Newcastle University, UK, have found. An image of watching eyes reduced the odds of littering by around two thirds.

Anxiety can kill your social status

Neuroscientists at EPFL identify a brain region that links anxious temperament to low social status. The researchers were able to tweak social hierarchy in animals by using vitamin B3.

Wiring rules untangle brain circuitry

Our brains contain billions of neurons linked through trillions of synaptic connections, and although disentangling this wiring may seem like mission impossible, a research team from Baylor College of Medicine took on the ...

Higher cigarette taxes linked to fewer infant deaths

Higher taxes and prices for cigarettes are strongly associated with lower infant mortality rates in the United States, according to a new study from Vanderbilt University and the University of Michigan released Dec. 1 in ...

Researchers grow retinal nerve cells in the lab

Johns Hopkins researchers have developed a method to efficiently turn human stem cells into retinal ganglion cells, the type of nerve cells located within the retina that transmit visual signals from the eye to the brain. ...