An international team of scientists has announced a breakthrough in the fight against malaria, paving the way for the development of new drugs to treat the deadly disease.
Medical research Nov 29, 2011 | 4.2 / 5 (6) | 3 |
Groundbreaking research from the Queensland Institute of Medical Research is set to pave the way for the development of new malaria drugs and vaccines.
Medical research Nov 25, 2011 | 5 / 5 (2) | 0
A study led by Hans Verhoef, a researcher at Wageningen University, the Netherlands, and the London School of Hygiene and Tropical Medicine, UK, and published in this week's PLoS Medicine shows that supplementing young Tanzan ...
Diseases, Conditions, Syndromes Nov 22, 2011 | not rated yet | 0
A study conducted by researchers at the Johns Hopkins Malaria Research Institute and their Zambian colleagues detected contrasting patterns of drug resistance in malaria-causing parasites taken from both humans and mosquitoes ...
Diseases, Conditions, Syndromes Nov 15, 2011 | not rated yet | 0 |
(Medical Xpress) -- Malaria is a disease caused by parasites passed to humans via the bites of infected mosquitoes. Globally, the disease causes over a million deaths every year, and is especially rife in ...
Medical research Nov 11, 2011 | 4.8 / 5 (16) | 2 |
For some time now, artemisinin, derived from a Chinese herb, has been the most powerful treatment available against malaria. To avoid the malaria parasite becoming resistant, the World Health Organisation (WHO) strongly recommends ...
Diseases, Conditions, Syndromes Nov 08, 2011 | not rated yet | 0
A new research technology is revealing how humans develop immunity to malaria, and could assist programs aimed at eradicating this parasitic disease.
Medical research Nov 01, 2011 | not rated yet | 1 |
A new malaria vaccine could be the first to tackle different forms of the disease and help those most vulnerable to infection, a study suggests.
Medical research Oct 26, 2011 | not rated yet | 1
Malaria is a major global health concern, and researchers are in need of new therapeutic approaches. To address this concern, a study published Oct. 26 in the online journal PLoS ONE reveals new information about the host c ...
Medical research Oct 26, 2011 | 5 / 5 (1) | 0
Researchers at the University of South Florida (USF) College of Public College Health have shown for the first time in a rodent model that the earliest form of malaria parasites can lay dormant in red blood cells and "wake ...
Medical research Oct 25, 2011 | not rated yet | 0 |
First results from a large-scale Phase III trial of RTS,S*, published online today in the New England Journal of Medicine (NEJM), show the malaria vaccine candidate to provide young African children with significant protec ...
Diseases, Conditions, Syndromes Oct 18, 2011 | not rated yet | 1
Nearly a third of all nations in which malaria is endemic are working to eliminate the disease within a decade, according to a new report released Monday in the United States.
Diseases, Conditions, Syndromes Oct 17, 2011 | not rated yet | 0
A new global atlas charts prospects for malaria elimination by offering the first full-color, detailed depiction of a disease now declining in many parts of the globe. The "Atlas of Malaria-Eliminating Countries" spotlights ...
Diseases, Conditions, Syndromes Oct 17, 2011 | 5 / 5 (1) | 0
Indoor spraying with the insecticide bendiocarb has dramatically decreased malaria transmission in many parts of Benin, new evidence that insecticides remain a potent weapon for fighting malaria in Africa despite the rapid ...
Diseases, Conditions, Syndromes Oct 05, 2011 | not rated yet | 0
Continuing a global effort to prevent malaria infections, Michigan State University researchers have created a new malaria vaccine one that combines the use of a disabled cold virus with an immune system-stimulating ...
Medical research Sep 26, 2011 | not rated yet | 0 |
Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases progressing to coma or death. It is widespread in tropical and subtropical regions, including much of Sub-Saharan Africa, Asia, and the Americas.
Five species of Plasmodium can infect and be transmitted by humans. Severe disease is largely caused by Plasmodium falciparum while the disease caused by Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae is generally a milder disease that is rarely fatal. Plasmodium knowlesi is a zoonosis that causes malaria in macaques but can also infect humans.
Malaria transmission can be reduced by preventing mosquito bites by distribution of mosquito nets and insect repellents, or by mosquito-control measures such as spraying insecticides and draining standing water (where mosquitoes breed). Despite a clear need, no vaccine offering a high level of protection currently exists. Efforts to develop one are ongoing. A number of medications are also available to prevent malaria in travelers to malaria-endemic countries (prophylaxis).
A variety of antimalarial medications are available. Severe malaria is treated with intravenous or intramuscular quinine or, since the mid-2000s, the artemisinin derivative artesunate, which is superior to quinine in both children and adults. Resistance has developed to several antimalarial drugs, most notably chloroquine.
There were an estimated 225 million cases of malaria worldwide in 2009. An estimated 655,000 people died from malaria in 2010, a 5% decrease from the 781,000 who died in 2009 according to the World Health Organization's 2011 World Malaria Report, accounting for 2.23% of deaths worldwide. Ninety percent of malaria-related deaths occur in sub-Saharan Africa, with ~60% of deaths being young children under the age of five. Plasmodium falciparum, the most severe form of malaria, is responsible for the vast majority of deaths associated with the disease. Malaria is commonly associated with poverty, and can indeed be a cause of poverty and a major hindrance to economic development.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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