Up to eight percent of malaria drugs approved by the World Health Organization or other regulators do not contain the right dose and may fuel resistance, researchers said Tuesday.
Medications Jul 10, 2012 | not rated yet | 0
Insecticide resistance is threatening the effectiveness of insecticide-treated bed nets and indoor insecticide sprays to control adult mosquito vectors, and so more sustainable integrated management strategies that use optimal ...
Diseases, Conditions, Syndromes Jul 10, 2012 | not rated yet | 0
A pair of provocative studies in the July 2012 issue of The American Journal of Tropical Medicine and Hygiene (AJTMH) provides a window into the intense ground war now underway against malaria. In one review, researchers offer ...
Diseases, Conditions, Syndromes Jul 03, 2012 | not rated yet | 1
(Medical Xpress) -- Infections from certain parasites can compromise the immune system, leaving it less able to fight other diseases.
Immunology Jun 28, 2012 | not rated yet | 0
Human insulin suppresses mosquito immune system: Increasing cases of type 2 diabetes could abet malaria's spread
Human insulin suppresses the mosquito immune system, according to a paper in the June Infection and Immunity. And while mosquitoes and malaria might seem to go together like baseball and hotdogs, mosquitoes' immunological resist ...
Immunology Jun 19, 2012 | not rated yet | 0
The health of a caregiver is the most important predictor of orphan health, according to a new Duke University study that spans five less-wealthy nations in Africa and Asia. More important than an orphan's geographic location, ...
Health Jun 13, 2012 | not rated yet | 0
Methods developed to enable large-scale analysis of malaria parasite genomes from patient blood samples
Researchers have developed a new technique to identify hotspots of malaria parasite evolution and track the rise of malarial drug resistance, faster and more efficiently than ever before.
Medical research Jun 13, 2012 | not rated yet | 0 |
Researchers at the Johns Hopkins Malaria Research Institute have, for the first time, determined the function of a series proteins within the mosquito that transduce a signal that enables the mosquito to fight off infection ...
Medical research Jun 07, 2012 | 5 / 5 (3) | 0 |
Giving young children medicine once a month during the rainy season to protect them against malaria could prevent tens of thousands of deaths each year in some areas of Africa, according to new research.
Diseases, Conditions, Syndromes Jun 06, 2012 | not rated yet | 0 |
A new technique that accurately determines the risk of infants in endemic countries developing clinical malaria could provide a valuable tool for evaluating new malaria prevention strategies and vaccines.
Diseases, Conditions, Syndromes Jun 05, 2012 | 5 / 5 (1) | 0 |
Reducing tuberculosis transmission in geographic "hotspots" where infections are highest could significantly reduce TB transmission on a broader scale, according to a study led by researchers at the Johns Hopkins Bloomberg ...
Diseases, Conditions, Syndromes May 28, 2012 | not rated yet | 0 |
A novel anti-inflammatory drug could help to improve survival in the most severe cases of malaria by preventing the immune system from causing irrevocable brain and tissue damage.
Diseases, Conditions, Syndromes May 23, 2012 | 5 / 5 (1) | 0 |
Poor-quality antimalarial drugs threaten to jeopardize progress made in malaria control over past decade
Poor-quality and fake antimalarial drugs are leading to drug resistance and inadequate treatment that is endangering global efforts made to control and eliminate malaria over the past 10 years, according to a review of the ...
Diseases, Conditions, Syndromes May 21, 2012 | not rated yet | 0
Researchers from Seattle Biomedical Research Institute (Seattle BioMed), the University of Copenhagen and the University of Edinburgh have uncovered new knowledge related to host-parasite interaction in severe malaria, concerning ...
Medical research May 21, 2012 | 5 / 5 (2) | 0 |
Clinical trials are urgently needed to test a new treatment that could jointly tackle leading causes of death for babies in sub-Saharan Africa, according to researchers from the London School of Hygiene & Tropical Medicine.
Diseases, Conditions, Syndromes May 15, 2012 | not rated yet | 0
Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases progressing to coma or death. It is widespread in tropical and subtropical regions, including much of Sub-Saharan Africa, Asia, and the Americas.
Five species of Plasmodium can infect and be transmitted by humans. Severe disease is largely caused by Plasmodium falciparum while the disease caused by Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae is generally a milder disease that is rarely fatal. Plasmodium knowlesi is a zoonosis that causes malaria in macaques but can also infect humans.
Malaria transmission can be reduced by preventing mosquito bites by distribution of mosquito nets and insect repellents, or by mosquito-control measures such as spraying insecticides and draining standing water (where mosquitoes breed). Despite a clear need, no vaccine offering a high level of protection currently exists. Efforts to develop one are ongoing. A number of medications are also available to prevent malaria in travelers to malaria-endemic countries (prophylaxis).
A variety of antimalarial medications are available. Severe malaria is treated with intravenous or intramuscular quinine or, since the mid-2000s, the artemisinin derivative artesunate, which is superior to quinine in both children and adults. Resistance has developed to several antimalarial drugs, most notably chloroquine.
There were an estimated 225 million cases of malaria worldwide in 2009. An estimated 655,000 people died from malaria in 2010, a 5% decrease from the 781,000 who died in 2009 according to the World Health Organization's 2011 World Malaria Report, accounting for 2.23% of deaths worldwide. Ninety percent of malaria-related deaths occur in sub-Saharan Africa, with ~60% of deaths being young children under the age of five. Plasmodium falciparum, the most severe form of malaria, is responsible for the vast majority of deaths associated with the disease. Malaria is commonly associated with poverty, and can indeed be a cause of poverty and a major hindrance to economic development.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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