Malignant Brain Tumors

Study suggests new treatment target for glioblastoma multiforme

A study by UT Southwestern Medical Center researchers published online today in Nature reveals new insight into why the most common, deadly kind of brain tumor in adults recurs and identifies a potential target ...

Cancer created Aug 01, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Key mutations discovered for medulloblastoma -- most common childhood brain cancer

Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) and several collaborating institutions have linked mutations in specific genes to each of the four recognized subtypes of medulloblastoma, the most common ...

Cancer created Jul 22, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers discover brain cancer treatment using genetic material from bone marrow cells

In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers at Henry Ford Hospital have discovered a novel approach for treatment of ...

Cancer created Apr 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study identifies growth factor essential to the most common malignant pediatric brain tumor

A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...

Cancer created Feb 28, 2013 | popularity not rated yet | comments 0 | with audio podcast

'Chemo brain': Study finds fog-like condition related to chemotherapy's effect on new brain cells and rhythms

(Medical Xpress)—It's not unusual for cancer patients being treated with chemotherapy to complain about not being able to think clearly, connect thoughts or concentrate on daily tasks. The complaint – ...

Neuroscience created Feb 21, 2013 | popularity not rated yet | comments 1 | with audio podcast

MicroRNA-218 targets medulloblastoma, most aggressive childhood brain cancer

Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the expression of faulty genes ...

Cancer created Dec 13, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Survival statistics show hard fight when malignant brain tumors appear at multiple sites

LOS ANGELES (Embargoed until 10 a.m. EDT on Aug. 24, 2012) – When aggressive, malignant tumors appear in more than one location in the brain, patient survival tends to be significantly shorter than when the disease starts ...

Neuroscience created Aug 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study: Vaccine targets malignant brain cancer antigens, significantly lengthens survival

An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Im ...

Immunology created Aug 15, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Identification of a novel target for glioblastoma treatment

(Medical Xpress) -- A recent study from scientists at the Friedrich Miescher Institute for Biomedical Research has identified a novel target for the treatment of malignant brain tumors. The scientists found ...

Cancer created Jun 18, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study explains fast tumor migration

(Phys.org) -- Bioengineering Professor Sanjay Kumar’s lab at the UC Berkeley today released major new research showing that tumor cells are able to migrate faster through confined spaces in the body.

Cancer created Jun 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

'Housekeeping' mechanism for brain stem cells discovered

Researchers at Columbia University Medical Center (CUMC) have identified a molecular pathway that controls the retention and release of the brain's stem cells. The discovery offers new insights into normal and abnormal neurologic ...

Neuroscience created Apr 22, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Discovery predicts patient sensitivity to important drug target in deadly brain cancer

A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma – the most common and most aggressive malignant brain tumor ...

Cancer created Feb 06, 2012 | popularity 4 / 5 (2) | comments 0 | with audio podcast

Defects in the packaging of DNA in malignant brain tumors

Glioblastomas grow extremely aggressively into healthy brain tissue and, moreover, are highly resistant to radiation therapy and chemotherapy. Therefore, they are regarded as the most malignant type of brain tumor. Currently ...

Cancer created Jan 30, 2012 | popularity not rated yet | comments 0 | with audio podcast

Old drugs find new target for treating brain tumor

Scientists at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center, in collaboration with colleagues in Boston and South Korea, say they have identified a novel ...

Cancer created Nov 18, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers find coupling of proteins promotes glioblastoma development

Two previously unassociated proteins known to be overly active in a variety of cancers bind together to ignite and sustain malignant brain tumors, a research team led by scientists at The University of Texas MD Anderson Cancer ...

Cancer created Oct 21, 2011 | popularity not rated yet | comments 0 | with audio podcast


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Researchers at the University of Wisconsin have identified a potential new risk factor for obstructive sleep apnea: asthma. Using data from the National Institutes of Health (Heart, Lung, and Blood Institute)-funded Wisconsin ...

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Computational tool translates complex data into simplified 2-dimensional images

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Ketamine shows significant therapeutic benefit in people with treatment-resistant depression

Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to-date led by researchers from the ...

Consuming coffee linked to lower risk of detrimental liver disease, study finds

Regular consumption of coffee is associated with a reduced risk of primary sclerosing cholangitis (PSC), an autoimmune liver disease, Mayo Clinic research shows. The findings were being presented at the Digestive Disease ...

Returning genetic incidental findings without patient consent violates basic rights, experts say

Informed consent is the backbone of patient care. Genetic testing has long required patient consent and patients have had a "right not to know" the results. However, as 21st century medicine now begins to use the tools of ...

Vicious cycle: Obesity sustained by changes in brain biochemistry

With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the st ...

White matter imaging provides insight into human and chimpanzee aging

(Medical Xpress)—The instability of "white matter" in humans may contribute to greater cognitive decline during the aging of humans compared with chimpanzees, scientists from Yerkes National Primate Research ...