Melanoma
Research breakthrough could halt melanoma metastasis
In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 ...
Cancer
Nov 14, 2012 |
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Cancer drug improves survival in patients with metastatic melanoma
(Medical Xpress)—Results of a University of Arizona Cancer Center's scientist-led clinical trial show that a drug already approved for breast and lung cancer improved progression-free survival in patients ...
Cancer
Nov 14, 2012 |
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Awareness could eliminate inequalities in cancer diagnoses
There are substantial inequalities in the stage at which cancer patients receive their diagnosis – a critical factor for cancer survival – a new study by the University of Cambridge reveals. The researchers found that ...
Cancer
Nov 12, 2012 |
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Moderately dysplastic nevi re-excision not necessary
(HealthDay)—Re-excision of mildly or moderately histologically dysplastic nevi (HDN) that approach a microscopic border may not be necessary, as favorable long-term outcomes are achieved without re-excision, ...
Diseases, Conditions, Syndromes
Nov 12, 2012 |
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Considerable added benefit of ipilimumab in advanced melanoma
The humanized antibody ipilimumab (trade name Yervoy) has been approved since August 2011 for the treatment of adult patients with advanced melanoma (black skin cancer) who have already been treated. The term "advanced" means ...
Cancer
Nov 09, 2012 |
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Spread of human melanoma cells in mice correlates with clinical outcomes in patients
UT Southwestern Medical Center scientists led by Dr. Sean Morrison, director of the Children's Medical Center Research Institute at UT Southwestern, have developed an innovative model for predicting the progression of skin ...
Cancer
Nov 07, 2012 |
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New monoclonal antibody inhibits tumor growth in advanced solid tumors in phase I clinical trial
A newly developed antibody targeting a signalling pathway that is frequently active in solid tumours has shown encouraging signs of efficacy in its first trial in humans, researchers will report at the 24th EORTC-NCI-AACR ...
Cancer
Nov 06, 2012 |
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Unexpected factor contributes to melanoma risk in red-haired, fair-skinned individuals
The well-established elevated risk of melanoma among people with red hair and fair skin may be caused by more than just a lack of natural protection against ultraviolet (UV) radiation. In an article receiving Advance Online ...
Cancer
Oct 31, 2012 |
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Recent findings may help to fight melanoma's resistance to chemotherapy
Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Instit ...
Cancer
Oct 31, 2012 |
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Negative pigment network able to distinguish melanoma
(HealthDay)—Negative pigment network (NPN) can be used to distinguish melanoma from Spitz nevus and other benign lesions, according to a study published online Oct. 11 in the Journal of the American Ac ...
Cancer
Oct 25, 2012 |
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Moffitt researchers identify unique immune gene signature across thousands of patients' solid tumors
(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered a unique immune gene signature that can predict the presence of microscopic lymph node-like structures in metastatic melanoma. The presence of these ...
Genetics
Oct 25, 2012 |
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Mouse model exposes a new type of T cell to target melanoma
Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers—or antigens—on cancer cells and destroy them before they grow ...
Cancer
Oct 24, 2012 |
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Alarming increase in malignant melanoma on the west coast of Sweden
Malignant melanoma is as much as 35% more common among people who live in Gothenburg and the region's coastal municipalities than those who live inland. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, ...
Cancer
Oct 22, 2012 |
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Researchers study 'ACT TIL' approach to treating metastatic melanoma
Researchers at Moffitt Cancer Center have carried out a clinical trial in which patients with metastatic melanoma were given chemotherapy and an immunotherapy of adoptive cell transfer (ACT) with tumor infiltrating lymphocytes ...
Immunology
Oct 17, 2012 |
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Researchers discover how melanoma cells circumvent the immune system
Melanoma is so dangerous because it tends to metastasize early on. New treatment approaches utilize, among other things, the ability of the immune defense to search out and destroy malignant cells. Yet this strategy is often ...
Cancer
Oct 10, 2012 |
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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.
Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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