Melanoma
Researchers building melanoma vaccine to combat skin cancer
Mayo Clinic researchers have trained mouse immune systems to eradicate skin cancer from within, using a genetic combination of human DNA from melanoma cells and a cousin of the rabies virus. The strategy, called cancer immunotherapy, ...
Cancer
Mar 19, 2012 |
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Researchers abuzz over caffeine as cancer-cell killer
(Medical Xpress)—Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells—results that could one day ...
Cancer
Apr 18, 2013 |
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Research breakthrough could halt melanoma metastasis
In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 ...
Cancer
Nov 14, 2012 |
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Melanoma: Whole-genome sequencing of 25 tumors confirms role of sun damage, reveals new genetic alterations
Melanoma the deadliest and most aggressive form of skin cancer has long been linked to time spent in the sun. Now a team led by scientists from the Broad Institute and Dana-Farber Cancer Institute has sequenced ...
Cancer
May 09, 2012 |
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Using patients' own tumor-fighting cells to knock back advanced melanoma
A small, early-phase clinical trial to test the effectiveness of treating patients with advanced melanoma using billions of clones of their own tumor-fighting cells combined with a specific type of chemotherapy has shown ...
Cancer
Mar 05, 2012 |
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Cancer vaccines self-sabotage, channel immune attack to injection site
Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson ...
Medical research
Mar 03, 2013 |
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Researchers engineer blood stem cells to fight melanoma
Researchers from UCLA's cancer and stem cell centers have demonstrated for the first time that blood stem cells can be engineered to create cancer-killing T-cells that seek out and attack a human melanoma. The researchers ...
Cancer
Nov 28, 2011 |
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New drug, Vemurafenib, doubles survival of metastatic melanoma patients
A report published this week in the New England Journal of Medicine shows that the 50 percent of metastatic melanoma patients with a specific genetic mutation benefit from the drug Vemurafenib increasing median surviv ...
Cancer
Mar 01, 2012 |
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Scientists uncover mechanism for melanoma drug resistance
Cancer is tough to kill and has many ways of evading the drugs used by oncologists to try and eliminate it.
Cancer
Mar 06, 2012 |
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New melanoma driver genes found in largest DNA sequencing study to date
(Medical Xpress) -- Yale Cancer Center geneticists, biochemists, and structural biologists have painted the most comprehensive picture yet of the molecular landscape of melanoma, a highly aggressive and often ...
Genetics
Jul 29, 2012 |
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Revolutionary techniques could help harness patients' own immune cells to fight disease
The human body contains immune cells programmed to fight cancer and viral infections, but they often have short lifespans and are not numerous enough to overcome attacks by particularly aggressive malignancies ...
Medical research
Jan 03, 2013 |
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Cloned receptor paves way for new breast and prostate cancer treatment
Researchers at Uppsala University have cloned a T-cell receptor that binds to an antigen associated with prostate cancer and breast cancer. T cells that have been genetically equipped with this T-cell receptor have the ability ...
Cancer
Sep 13, 2012 |
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Study reveals trigger that may speed melanoma growth
(HealthDay) -- Growth of the deadly skin cancer melanoma may be triggered by the immune system turning on itself, according to a new study that also identified the mechanism that causes this to happen.
Cancer
Mar 28, 2012 |
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Study identifies human melanoma stem cells
(Medical Xpress)—Cancer stem cells are defined by three abilities: differentiation, self-renewal and their ability to seed a tumor. These stem cells resist chemotherapy and many researchers posit their ...
Cancer
Aug 23, 2012 |
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Bioelectric signals can be used to detect early cancer
Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower ...
Medical research
Feb 01, 2013 |
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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.
Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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