Melanoma

Study reveals how melanoma evades chemotherapy

Nitric oxide (NO), a gas with many biological functions in healthy cells, can also help some cancer cells survive chemotherapy. A new study from MIT reveals one way in which this resistance may arise, and ...

Cancer created Apr 08, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New target plus new drug equals death of melanoma cells

Collaborative research presented by the University of Colorado Cancer Center, the University of North Carolina at Chapel Hill, Harvard Medical School and the University of Pittsburgh, at the American Association for Cancer ...

Cancer created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0

Naturally occurring substance proves effective against deadly skin cancer in laboratory tests

For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin ...

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

Report finds continuing challenges in changing behaviors that increase cancer risk

An annual report from the American Cancer Society finds continuing challenges in changing behaviors and risk factors in order to reduce suffering and death from cancer. The report, Cancer Prevention & Early Detection Facts ...

Cancer created Apr 11, 2013 | popularity 5 / 5 (1) | comments 0

Two-pronged approach to immune activation could lead to vaccines that effectively shut down tumor expansion

Tumor cells often express proteins that set them apart from their healthy neighbors. These very same proteins can also help the immune system to recognize and destroy the cancer. Several research groups and ...

Cancer created Apr 26, 2013 | popularity 5 / 5 (1) | comments 0

Scientists discover new target for personalized cancer therapy

A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a ...

Cancer created May 02, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New drug targets skin cancer

A new class of drug targeting skin cancer's genetic material has been successfully tested in humans for the first time, opening the way to new treatments for a range of conditions from skin cancers to eye ...

Cancer created May 07, 2013 | popularity 5 / 5 (1) | comments 0

Discovery of gene mutation causing Sturge-Weber syndrome, port-wine stain birthmarks offers new hope

In new findings published on May 8, 2013 in the New England Journal of Medicine (Epub ahead of print), researchers from the Kennedy Krieger Institute reveal the discovery of the cause – a genetic mutation that occurs before ...

Genetics created May 08, 2013 | popularity 5 / 5 (1) | comments 0

Animals in research: Zebrafish

Zebrafish are probably not the first creatures that come to mind when it comes to animals that are valuable for medical research.

Medical research created May 10, 2013 | popularity 5 / 5 (1) | comments 0

Skin cancer may be linked to lower risk of Alzheimer's disease

People who have skin cancer may be less likely to develop Alzheimer's disease, according to new research published in the May 15, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. The li ...

Alzheimer's disease & dementia created May 15, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Infusing chemotherapy into the liver gives extra months of disease-free life in melanoma patients

Melanoma of the eye (ocular or uveal melanoma) frequently spreads to the liver and, once this has happened, there is no effective treatment and patients die within an average of two to four months. Only about one in ten patients ...

Cancer created Sep 23, 2011 | popularity 4 / 5 (1) | comments 0

Systemic tumor disappearance following local radiation treatment reported in metastatic melanoma patient

A rarely seen phenomenon in cancer patients — in which focused radiation to the site of one tumor is associated with the disappearance of metastatic tumors all over the body — has been reported in a patient with ...

Cancer created Mar 07, 2012 | popularity 4 / 5 (1) | comments 0

Alarming increase in malignant melanoma on the west coast of Sweden

Malignant melanoma is as much as 35% more common among people who live in Gothenburg and the region's coastal municipalities than those who live inland. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, ...

Cancer created Oct 22, 2012 | popularity 4 / 5 (1) | comments 0

New peri-op approach accurately IDs melanoma in nail matrix

(HealthDay) -- Intraoperative reflectance confocal microscopy (RCM) can be used to diagnose melanonychia striata in the nail matrix, according to a study published online June 7 in the British Journal of De ...

Cancer created Jun 14, 2012 | popularity 3 / 5 (1) | comments 0

Study examines association between Parkinson disease, cancer

A study that used a Utah genealogic database and a statewide cancer registry to examine the relationship between Parkinson disease (PD) and cancer suggests an increased risk of prostate cancer and melanoma in patients with ...

Parkinson's & Movement disorders created Sep 03, 2012 | popularity 3 / 5 (1) | comments 0 | with audio podcast


Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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