Melanoma

Research on immune-cell therapy could strengthen promising melanoma treatment

A new study of genetically modified immune cells by scientists from UCLA and the California Institute of Technology could help improve a promising treatment for melanoma, an often fatal form of skin cancer.

Cancer created Mar 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

Tapeworm DNA contains drug weak spots

For the first time, researchers have mapped the genomes of tapeworms to reveal potential drug targets on which existing drugs could act. The genomes provide a new resource that offers faster ways to develop urgently needed ...

Diseases, Conditions, Syndromes created Mar 13, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Aspirin may lower melanoma risk

A new study has found that women who take aspirin have a reduced risk of developing melanoma—and that the longer they take it, the lower the risk. The findings suggest that aspirin's anti-inflammatory effects may help protect ...

Cancer created Mar 11, 2013 | popularity not rated yet | comments 1 | with audio podcast

BRAF inhibitor treatment causes melanoma cells to shift how they produce energy

A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...

Cancer created Mar 08, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Hope in stopping melanoma from spreading: Study shows that inhibiting key protein prevents metastasis to lungs in mice

(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation ...

Cancer created Mar 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Cancer vaccines self-sabotage, channel immune attack to injection site

Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson ...

Medical research created Mar 03, 2013 | popularity 4.8 / 5 (5) | comments 1 | with audio podcast

New cancer 'vaccine' shows future promise in treating and preventing metastatic cancers

Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center. Results from ...

Cancer created Feb 27, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Taking omega-3 supplements may help prevent skin cancer, new study finds

(Medical Xpress)—Taking omega-3 fish oils could help to protect against skin cancer, according to researchers at The University of Manchester. The team has just carried out the first clinical trial to examine the impact ...

Cancer created Feb 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Gene identified in some melanoma linked to increased resistance to treatment

(Medical Xpress)—Scientists at Queen Mary, University of London have identified a gene present in some melanoma which appears to make the tumour cells more resistant to treatment, according to research ...

Cancer created Feb 19, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Early results show two drugs may be better than one to treat most deadly skin cancer

Adding lung cancer drugs to targeted melanoma treatment could increase survival for certain patients, according to research published in Cancer Discovery today.

Cancer created Feb 12, 2013 | popularity not rated yet | comments 0 | with audio podcast

Steroids help reverse rapid bone loss tied to rib fractures

New research in animals triggered by a combination of serendipity and counterintuitive thinking could point the way to treating fractures caused by rapid bone loss in people, including patients with metastatic ...

Medical research created Feb 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Immune system can use melanoma's own proteins to kill off cancer cells

Though a small group of proteins, the family called Ras controls a large number of cellular functions, including cell growth, differentiation, and survival. And because the protein has a hand in cellular division, mutated ...

Cancer created Feb 04, 2013 | popularity not rated yet | comments 0 | with audio podcast

Bioelectric signals can be used to detect early cancer

Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower ...

Medical research created Feb 01, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Study reveals two-fold higher incidence of non-melanoma skin cancers for HIV patients

HIV-positive patients have a higher incidence of non-melanoma skin cancers, according to a Kaiser Permanente study that appears in the current online issue of the Journal of the National Cancer Institute. Specifically, basal ...

Cancer created Jan 29, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Sunbed skin cancer risk double that of Mediterranean midday summer sun

(Medical Xpress)—The average skin cancer risk from sunbeds is more than double that of spending the same length of time in the Mediterranean midday summer sun – according to new research from the University ...

Cancer created Jan 17, 2013 | popularity not rated yet | comments 0 | with audio podcast


Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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