Metastatic Melanoma
Cancerous tumors deliver pro-metastatic information in secreted vesicles
Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called ...
Cancer
May 29, 2012 |
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New drug shrinks brain tumours in melanoma patients
(Medical Xpress) -- Australian researchers have reported promising results with a new drug that shrinks brain tumours in melanoma patients. Their findings are published in The Lancet medical journal today. ...
Cancer
May 21, 2012 |
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ASCO: Dabrafenib/Trametinib active in metastatic melanoma
(HealthDay) -- For patients with V600 BRAF-mutant solid tumors, treatment with the oral BRAF inhibitor dabrafenib and the oral MEK 1/2 inhibitor trametinib is tolerated and has clinical activity in BRAF inh ...
Cancer
May 17, 2012 |
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Melanoma: Whole-genome sequencing of 25 tumors confirms role of sun damage, reveals new genetic alterations
Melanoma – the deadliest and most aggressive form of skin cancer – has long been linked to time spent in the sun. Now a team led by scientists from the Broad Institute and Dana-Farber Cancer Institute has sequenced ...
Cancer
May 09, 2012 |
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Immunotherapy and chemotherapy regimen may prolong survival in advanced cancers
Maintenance therapy with interleukin-2 and 13-cis retinoic acid may be an inexpensive method for increasing survival in patients with a variety of stage 4 cancers, according to data reported at the AACR Annual Meeting 2012, ...
Cancer
Apr 03, 2012 |
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Second mutation in BRAF-mutated melanoma doesn't contribute to resistance
A second mutation found in the tumors of patients with BRAF-mutated metastatic melanoma does not contribute to resistance to BRAF inhibitor drugs, a finding that runs counter to what scientists expected to be true.
Cancer
Apr 01, 2012 |
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Scientists boost potency, reduce side effects of IL-2 protein used to treat cancer
The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist ...
Medical research
Mar 18, 2012 |
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Response rate high for some patients with metastatic melanoma treated with vemurafenib
An international team of researchers from the United States and Australia, including researchers at Moffitt Cancer Center in Tampa, Fla., have found that the oral BRAF inhibitor vemurafenib (PLX4032) when tested in a phase ...
Cancer
Mar 16, 2012 |
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Bright future ahead for antibody cancer therapy
Antibodies, once touted as the "magic bullets" of cancer care, are now fulfilling that promise and more advances are on the way, say cancer researchers at the Georgetown Lombardi Comprehensive Cancer Center
Cancer
Mar 15, 2012 |
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Systemic tumor disappearance following local radiation treatment reported in metastatic melanoma patient
A rarely seen phenomenon in cancer patients — in which focused radiation to the site of one tumor is associated with the disappearance of metastatic tumors all over the body — has been reported in a patient with ...
Cancer
Mar 07, 2012 |
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Researchers report progress in cancer immunotherapy
In a bid to make cancer immunotherapy more effective, researchers report they have succeeded in halting the progress of aggressive melanoma in its tracks - at least briefly - in seven patients treated with an army of cloned ...
Cancer
Mar 06, 2012 |
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Scientists uncover mechanism for melanoma drug resistance
Cancer is tough to kill and has many ways of evading the drugs used by oncologists to try and eliminate it.
Cancer
Mar 06, 2012 |
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Using patients' own tumor-fighting cells to knock back advanced melanoma
A small, early-phase clinical trial to test the effectiveness of treating patients with advanced melanoma using billions of clones of their own tumor-fighting cells combined with a specific type of chemotherapy has shown ...
Cancer
Mar 05, 2012 |
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New drug, Vemurafenib, doubles survival of metastatic melanoma patients
A report published this week in the New England Journal of Medicine shows that the 50 percent of metastatic melanoma patients with a specific genetic mutation benefit from the drug Vemurafenib – increasing median surviv ...
Cancer
Mar 01, 2012 |
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New melanoma drug Zelboraf nearly doubles survival in majority of patients
Investigators from Vanderbilt-Ingram Cancer Center (VICC) and 12 other centers in the United States and Australia have found that a new drug for patients with metastatic melanoma nearly doubled median overall survival.
Cancer
Feb 22, 2012 |
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Latest Spotlight News
New immune system discovered
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
Brain can be trained in compassion, study shows
Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.
Hormone levels may provide key to understanding psychological disorders in women
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
Do salamanders hold the solution to regeneration?
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
Multiple research teams unable to confirm high-profile Alzheimer's study
Teams of highly respected Alzheimer's researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science.
Controlling mood through the motions of mitochondria
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...
Motion quotient: IQ predicted by ability to filter motion (w/ video)
A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...
Brain uses internal 'average voice' prototype to identify who is talking
(Medical Xpress)—The human brain is able to identify individuals' voices by comparing them against an internal 'average voice' prototype, according to neuroscientists.
The compound in the Mediterranean diet that makes cancer cells 'mortal'
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
Slowing the aging process—only with antibiotics
Swiss scientists reveal the mechanism responsible for aging hidden deep within mitochondria—and dramatically slow it down in worms by administering antibiotics to the young.
