Mitochondrial Dysfunction
Researchers identify Parkinson's disease link
(Medical Xpress)—Researchers at the Virginia Commonwealth University Parkinson's and Movement Disorders Center have found that mitochondrial quality and functional capacity play an important role in Parkinson's ...
Parkinson's & Movement disorders
Mar 19, 2013 |
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Mutations in VCP gene implicated in a number of neurodegenerative diseases
New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone a ...
Neuroscience
Mar 14, 2013 |
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Cell metabolism: Muscle loss can be caused by mitochondrial degradation induced by protein Mul1
Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide ...
Medical research
Mar 13, 2013 |
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Compound developed by scientists protects heart cells during and after attack
Using two different compounds they developed, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to show in animal models that inhibiting a specific enzyme protects heart cells and ...
Cardiology
Feb 07, 2013 |
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Link found between insulin sensitivity, cells' powerhouses
If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat ...
Medical research
Jan 29, 2013 |
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UCI study reveals why Down syndrome boosts susceptibility to other conditions
A study led by UC Irvine researchers has revealed some of the underlying neural factors that explain why people with Down syndrome are more susceptible to Alzheimer's disease, diabetes and autistic spectrum disorders.
Alzheimer's disease & dementia
Jan 11, 2013 |
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Scientists uncover potential drug target to block cell death in Parkinson's disease
Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer's disease, Amyotrophic Lateral Sclerosis and Parkinson's disease. Now, scientists from the Florida campus of ...
Parkinson's & Movement disorders
Jan 10, 2013 |
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Arthritis cartilage shows mitochondrial dysfunction
(HealthDay)—Cartilage from osteoarthritis patients shows greater oxidative damage and mitochondrial dysfunction than healthy cartilage, which is associated with the downregulation of the superoxide dismutase ...
Arthritis & Rheumatism
Nov 19, 2012 |
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Hepatitis C treatment's side effects can now be studied in the lab
(Medical Xpress)—The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg ...
Diseases, Conditions, Syndromes
Nov 16, 2012 |
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Key discovered to how chemotherapy drug causes heart failure
Doxorubicin, a 50-year-old chemotherapy drug still in widespread use against a variety of cancers, has long been known to destroy heart tissue, as well as tumors, in some patients.
Cancer
Oct 28, 2012 |
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Metabolic patterns of propofol, sevoflurane differ in children
(HealthDay)—For children undergoing routine anesthesia for medically indicated magnetic resonance imaging (MRI), the metabolic signature varies with use of sevoflurane and propofol, according to a study ...
Other
Oct 26, 2012 |
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Researchers identifie gatekeeper protein, new details on cell's power source
Researchers at Temple University's Center for Translational Medicine and the University of Pennsylvania have identified a protein that serves as a gatekeeper for controlling the rush of calcium into the cell's power source, ...
Medical research
Oct 25, 2012 |
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For mitochondria, bigger may not be better
Goldilocks was on to something when she preferred everything "just right." Harvard Medical School researchers have found that when it comes to the length of mitochondria, the power-producing organelles, applying the fairy ...
Medical research
Aug 23, 2012 |
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How aging normal cells fuel tumor growth and metastasis
It has long been known that cancer is a disease of aging, but a molecular link between the two has remained elusive.
Cancer
Jun 14, 2012 |
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Out of the shadows: Freeing families from mitochondrial inherited disease
(Medical Xpress) -- Mitochondrial inherited diseases (MIDs) can devastate families, but there is hope in the form of new techniques to prevent them passing from mother to child. Anjana Ahuja speaks to the ...
Medical research
Jun 12, 2012 |
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Latest Spotlight News
'Gap' for HIV vaccine efforts after latest setback
The hunt for an HIV vaccine has gobbled up $8 billion in the past decade, and the failure of the most recent efficacy trial has delivered yet another setback to 26 years of efforts.
Consuming coffee linked to lower risk of detrimental liver disease, study finds
Regular consumption of coffee is associated with a reduced risk of primary sclerosing cholangitis (PSC), an autoimmune liver disease, Mayo Clinic research shows. The findings were being presented at the Digestive Disease ...
Ketamine shows significant therapeutic benefit in people with treatment-resistant depression
Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to-date led by researchers from the ...
New research identifies risks, interventions for children's GI health
An increasing number of U.S. children are experiencing gastrointestinal issues that require interventions to resolve, according to research presented at Digestive Disease Week (DDW).
Returning genetic incidental findings without patient consent violates basic rights, experts say
Informed consent is the backbone of patient care. Genetic testing has long required patient consent and patients have had a "right not to know" the results. However, as 21st century medicine now begins to use the tools of ...
Vicious cycle: Obesity sustained by changes in brain biochemistry
With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the st ...
White matter imaging provides insight into human and chimpanzee aging
(Medical Xpress)—The instability of "white matter" in humans may contribute to greater cognitive decline during the aging of humans compared with chimpanzees, scientists from Yerkes National Primate Research ...
Melon focus headband turns to Kickstarter for rollout plans
(Medical Xpress)—What if the quality of your work depends more on your focus on the piano keys or canvas or laptop than your musical or painting or computing skills? If target users can be convinced, they ...
Temporal processing in the olfactory system
The neural machinery underlying our olfactory sense continues to be an enigma for neuroscience. A recent review in Neuron seeks to expand traditional ideas about how neurons in the olfactory bulb might encode information about ...
AIDS science at 30: 'Cure' now part of lexicon
Big names in medicine are set to give an upbeat assessment of the war on AIDS on Tuesday, 30 years after French researchers identified the virus that causes the disease.
