Mitochondrial Dysfunction
Researchers identify Parkinson's disease link
(Medical Xpress)—Researchers at the Virginia Commonwealth University Parkinson's and Movement Disorders Center have found that mitochondrial quality and functional capacity play an important role in Parkinson's ...
Parkinson's & Movement disorders
Mar 19, 2013 |
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Mutations in VCP gene implicated in a number of neurodegenerative diseases
New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone a ...
Neuroscience
Mar 14, 2013 |
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Cell metabolism: Muscle loss can be caused by mitochondrial degradation induced by protein Mul1
Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide ...
Medical research
Mar 13, 2013 |
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Compound developed by scientists protects heart cells during and after attack
Using two different compounds they developed, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to show in animal models that inhibiting a specific enzyme protects heart cells and ...
Cardiology
Feb 07, 2013 |
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Link found between insulin sensitivity, cells' powerhouses
If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat ...
Medical research
Jan 29, 2013 |
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UCI study reveals why Down syndrome boosts susceptibility to other conditions
A study led by UC Irvine researchers has revealed some of the underlying neural factors that explain why people with Down syndrome are more susceptible to Alzheimer's disease, diabetes and autistic spectrum disorders.
Alzheimer's disease & dementia
Jan 11, 2013 |
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Scientists uncover potential drug target to block cell death in Parkinson's disease
Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer's disease, Amyotrophic Lateral Sclerosis and Parkinson's disease. Now, scientists from the Florida campus of ...
Parkinson's & Movement disorders
Jan 10, 2013 |
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Arthritis cartilage shows mitochondrial dysfunction
(HealthDay)—Cartilage from osteoarthritis patients shows greater oxidative damage and mitochondrial dysfunction than healthy cartilage, which is associated with the downregulation of the superoxide dismutase ...
Arthritis & Rheumatism
Nov 19, 2012 |
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Hepatitis C treatment's side effects can now be studied in the lab
(Medical Xpress)—The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg ...
Diseases, Conditions, Syndromes
Nov 16, 2012 |
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Key discovered to how chemotherapy drug causes heart failure
Doxorubicin, a 50-year-old chemotherapy drug still in widespread use against a variety of cancers, has long been known to destroy heart tissue, as well as tumors, in some patients.
Cancer
Oct 28, 2012 |
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Metabolic patterns of propofol, sevoflurane differ in children
(HealthDay)—For children undergoing routine anesthesia for medically indicated magnetic resonance imaging (MRI), the metabolic signature varies with use of sevoflurane and propofol, according to a study ...
Other
Oct 26, 2012 |
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Researchers identifie gatekeeper protein, new details on cell's power source
Researchers at Temple University's Center for Translational Medicine and the University of Pennsylvania have identified a protein that serves as a gatekeeper for controlling the rush of calcium into the cell's power source, ...
Medical research
Oct 25, 2012 |
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For mitochondria, bigger may not be better
Goldilocks was on to something when she preferred everything "just right." Harvard Medical School researchers have found that when it comes to the length of mitochondria, the power-producing organelles, applying the fairy ...
Medical research
Aug 23, 2012 |
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How aging normal cells fuel tumor growth and metastasis
It has long been known that cancer is a disease of aging, but a molecular link between the two has remained elusive.
Cancer
Jun 14, 2012 |
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Out of the shadows: Freeing families from mitochondrial inherited disease
(Medical Xpress) -- Mitochondrial inherited diseases (MIDs) can devastate families, but there is hope in the form of new techniques to prevent them passing from mother to child. Anjana Ahuja speaks to the ...
Medical research
Jun 12, 2012 |
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Latest Spotlight News
New immune system discovered
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
Brain can be trained in compassion, study shows
Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.
Do salamanders hold the solution to regeneration?
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
Hormone levels may provide key to understanding psychological disorders in women
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
Multiple research teams unable to confirm high-profile Alzheimer's study
Teams of highly respected Alzheimer's researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science.
The compound in the Mediterranean diet that makes cancer cells 'mortal'
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
Brain uses internal 'average voice' prototype to identify who is talking
(Medical Xpress)—The human brain is able to identify individuals' voices by comparing them against an internal 'average voice' prototype, according to neuroscientists.
Motion quotient: IQ predicted by ability to filter motion (w/ video)
A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...
Controlling mood through the motions of mitochondria
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...
Slowing the aging process—only with antibiotics
Swiss scientists reveal the mechanism responsible for aging hidden deep within mitochondria—and dramatically slow it down in worms by administering antibiotics to the young.
