Motor Neurone Disease

Neurons' broken machinery piles up in ALS

A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If it cannot, the defective components pile up and the cell becomes sick ...

Aug 12, 2015
popularity20 comments 0

The motor neurone diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including speaking, walking, breathing, swallowing and general movement of the body. They are generally progressive in nature, and can cause progressive disability and death. The drug riluzole can slow progression slightly; apart from this the medical care is supportive. The condition was first described in full by the French neurologist Jean-Martin Charcot in 1869.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

New type of prion may cause, transmit neurodegeneration

Multiple System Atrophy (MSA), a neurodegenerative disorder with similarities to Parkinson's disease, is caused by a newly discovered type of prion, akin to the misfolded proteins involved in incurable progressive brain diseases ...

Older people getting smarter, but not fitter

Older populations are scoring better on cognitive tests than people of the same age did in the past —a trend that could be linked to higher education rates and increased use of technology in our daily lives, say IIASA population ...

We've all got a blind spot, but it can be shrunk

You've probably never noticed, but the human eye includes an unavoidable blind spot. That's because the optic nerve that sends visual signals to the brain must pass through the retina, which creates a hole in that light-sensitive ...

Epigenomic changes are key to innate immunological memory

A research team led by Keisuke Yoshida and Shunsuke Ishii of the RIKEN Molecular Genetics Laboratory has revealed that epigenomic changes induced by pathogen infections, mediated by a transcription factor called ATF7, are ...