Muscle Degeneration
Promoting muscle regeneration in a mouse model of muscular dystrophy
Duchenne muscular dystrophy (DMD) is a degenerative skeletal muscle disease caused by mutations in the protein dystrophin. Dystrophin functions to protect muscle cells from injury and loss of functional dystrophin results ...
Medical research
Apr 01, 2013 |
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New findings on heat shock proteins may shed light on variety of debilitating diseases
UCLA researchers, in a finding that runs counter to conventional wisdom, have discovered for the first time that a gene thought to express a protein in all cells that come under stress is instead expressed only in specific ...
Medical research
Jan 29, 2013 |
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Tamoxifen ameliorates symptoms of Duchenne muscular dystrophy
A new study has found that tamoxifen, a well-known breast cancer drug, can counteract some pathologic features in a mouse model of Duchenne muscular dystrophy (DMD). At present, no treatment is known to produce ...
Diseases, Conditions, Syndromes
Jan 15, 2013 |
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Scientists find drug that may help fight duchenne muscular dystrophy
Drugs are currently being tested that show promise in treating patients with Duchenne muscular dystrophy (DMD), an inherited disease that affects about one in 3,600 boys and results in muscle degeneration and, eventually, ...
Medical research
Dec 12, 2012 |
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New vitamin-based treatment that could reduce muscle degeneration in muscular dystrophy
Boosting the activity of a vitamin-sensitive cell adhesion pathway has the potential to counteract the muscle degeneration and reduced mobility caused by muscular dystrophies, according to a research team led by scientists ...
Medical research
Oct 23, 2012 |
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Novel discovery links anti-cancer drugs to muscle repair
Few drugs are available to treat muscle injury, muscle wasting and genetic disorders causing muscle degeneration, such as Duchenne muscular dystrophy. A compelling discovery that may change this was made recently by a research ...
Medical research
Oct 16, 2012 |
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Researchers solve key part of old mystery in generating muscle mass
Working with mice, Johns Hopkins researchers have solved a key part of a muscle regeneration mystery plaguing scientists for years, adding strong support to the theory that muscle mass can be built without ...
Medical research
Sep 27, 2012 |
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Strong communication between brain and muscle requires both having the protein LRP4
Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues ...
Neuroscience
Jul 11, 2012 |
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Researchers identify genetic mutation causing rare form of spinal muscular atrophy
Scientists have confirmed that mutations of a gene are responsible for some cases of a rare, inherited disease that causes progressive muscle degeneration and weakness: spinal muscular atrophy with lower extremity predominance, ...
Neuroscience
May 10, 2012 |
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Tweaking a gene makes muscles twice as strong
A team of researchers at EPFL, the University of Lausanne and the Salk Institute created super strong, marathon mice and nematodes by reducing the function of a natural inhibitor, suggesting treatments for ...
Genetics
Nov 10, 2011 |
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Failure in nerve-fiber navigation corrected in zebrafish model, suggests possibility of drug treatment
Spinal muscular atrophy (SMA) is the leading genetic cause of death in children under 2, with no treatment other than supportive care. In the Proceedings of the National Academy of Sciences, researchers at Children's Hospit ...
Medical research
Jun 06, 2011 |
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