Alzheimer's disease & dementia

Researchers find new target for Alzheimer's drug development

Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.

Alzheimer's disease & dementia

Astrocytes as a novel target in Alzheimer's disease

Alzheimer's disease is a severe neurodegenerative disease that affects 45% of people over 85 years of age. The research teams of Prof. Jin-Moo Lee at Washington University in Saint Louis, USA, and Prof. Milos Pekny at Sahlgrenska ...

Alzheimer's disease & dementia

Researchers identify new enzyme to fight Alzheimer's disease

An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme—known as BACE2—destroys beta-amyloid, a toxic protein fragment ...

Alzheimer's disease & dementia

Vitamin C and beta-carotene might protect against dementia

Forgetfulness, lack of orientation, cognitive decline… about 700, 000 Germans suffer from Alzheimer's disease (AD). Now researchers from the University of Ulm, among them the Epidemiologist Professor Gabriele Nagel and ...

Medical research

Detector of DNA damage: Structure of a repair factor revealed

Double-stranded breaks in cellular DNA can trigger tumorigenesis. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich, Germany, have determined the structure of a protein involved in the repair and signaling ...

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