Neurodegenerative Diseases

Proteases help nerve cells to navigate

Our ability to move relies on the correct formation of connections between different nerve cells and between nerve and muscle cells. Growing axons of nerve cells are guided to their targets by signposts expressed ...

23 hours ago
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Exercise can improve memory in 60-year-olds

A new study, in which researchers from Karolinska Institutet participated, shows that physical activity can improve memory performance in older people through increasing volume and blood flow in an area of the brain called ...

Oct 14, 2014
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Study reveals novel role for the Pin1 molecule

Synapses are "dynamic" things: they can regulate their action in neural processes related to learning, for example, but also as a consequence of diseases. A research team – led by SISSA – has demonstrated ...

Oct 10, 2014
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How rabies "hijacks" neurons to attack the brain

Rabies causes acute inflammation of the brain, producing psychosis and violent aggression. The virus, which paralyzes the body's internal organs, is always deadly for those unable to obtain vaccines in time. ...

Oct 06, 2014
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Applying proteomics to Parkinson's

(Medical Xpress)—Scientists studying two genes that are mutated in an early-onset form of Parkinson's disease have deciphered how normal versions of these genes collaborate to help rid cells of damaged ...

Oct 03, 2014
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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases including Parkinson’s, Alzheimer’s, and Huntington’s occur as a result of neurodegenerative processes. As research progresses, many similarities appear which relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously. There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death. Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.

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