Medical research

A potential active ingredient for nerve regeneration

Nerve fibers (axons) transmit brain and spinal cord signals through nerves to target muscles or skin, and vice versa. Damage to these fibers thus leads to a disruption of connections and, consequently, to paralysis or numbness. ...

Health

This is how tobacco damages our cells

My father smoked a pipe for some time, and I vividly remember that sticky black substance—tar—which stuck to the device's filter. Now imagine this stuff going into your lungs, and coating their walls. The picture is unpleasant, ...

Medications

Gabapentinoids associated with severe exacerbation of COPD

A population-based cohort study of more than 10,000 persons using gabapentinoids found that their use was associated with an increased risk of chronic obstructive pulmonary disease (COPD) exacerbation. This study supports ...

Diseases, Conditions, Syndromes

All pain is not the same when it comes to MS

Pain can present itself in many forms for people battling multiple sclerosis, and one type can interfere with exercising, new research shows.

Medications

New potential drug suppresses chemotherapy-induced pain

Oncode Investigator Mario van der Stelt and his lab discovered a potential new drug that suppresses chemotherapy-induced neuropathic pain. The results are published in Nature Communications.

Health

It may not be too late to get your HPV vaccine

Kentucky has the highest rate of cancers caused by the human papillomavirus (HPV) in the U.S.—a dire statistic considering these cancers can be largely preventable through vaccination.

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Neuropathic pain results from lesions or diseases affecting the somatosensory system. It may be associated with abnormal sensations called dysesthesia, which occur spontaneously and allodynia that occurs in response to external stimuli. Neuropathic pain may have continuous and/or episodic (paroxysmal) components. The latter are likened to an electric shock. Common qualities include burning or coldness, "pins and needles" sensations, numbness and itching. Nociceptive pain, by contrast, is more commonly described as aching.

Up to 7% to 8% of the European population is affected and in 5% of persons it may be severe. Neuropathic pain may result from disorders of the peripheral nervous system or the central nervous system (brain and spinal cord). Thus, neuropathic pain may be divided into peripheral neuropathic pain, central neuropathic pain, or mixed (peripheral and central) neuropathic pain.

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