Neuropathic Pain

Drugs similar in efficacy for neuropathic pain in diabetes

(HealthDay)—In the treatment of patients with chronic diabetic peripheral neuropathic pain (DPNP), there are no significant differences in pain-relief efficacy between amitriptyline, duloxetine, and pregabalin; however, ...

Diabetes created Sep 26, 2012 | popularity 5 / 5 (1) | comments 0

Researchers investigating potential drug for treatement of Alzheimer's disease

A compound developed to treat neuropathic pain has shown potential as an innovative treatment for Alzheimer's disease, according to a study by researchers at Cleveland Clinic's Lerner Research Institute and Anesthesiology ...

Alzheimer's disease & dementia created Aug 31, 2012 | popularity not rated yet | comments 0

Positive news for shingles pain sufferers

A new treatment from a University of Queensland start-up company, Spinifex Pharmaceuticals, could bring hope to shingles sufferers experiencing nerve pain.

Diseases, Conditions, Syndromes created Aug 29, 2012 | popularity 5 / 5 (1) | comments 0

Widely used drug could offer substantial relief to people with chronic cough

New research published Online First in the Lancet is the first to show that gabapentin, a drug widely used to treat pain and seizures, substantially reduces the frequency and severity of coughing and other symptoms associ ...

Diseases, Conditions, Syndromes created Aug 27, 2012 | popularity not rated yet | comments 0

Researchers identify which sensory nerve cells contribute to chronic nerve pain

(Medical Xpress) -- New research from the University of Bristol has identified the subtypes of sensory nerve cells that are likely to contribute to long-term nerve pain from partial nerve injury. It is hoped ...

Medical research created Aug 17, 2012 | popularity 4 / 5 (1) | comments 1 | with audio podcast

Off-label drug use common, but patients may not know they're taking them, study finds

Many people have probably heard of off-label drug use, but they may not know when that applies to prescriptions they are taking, a Mayo Clinic analysis found. Off-label drug use occurs when a physician prescribes medication ...

Medications created Aug 06, 2012 | popularity not rated yet | comments 0

GlaxoSmithKline to pay $3 billion for health fraud

(AP) — GlaxoSmithKline LLC will pay $3 billion and plead guilty to promoting two popular drugs for unapproved uses and to failing to disclose important safety information on a third in the largest health ...

Other created Jul 02, 2012 | popularity not rated yet | comments 0

Discovery could help combat chronic pain in diabetics

(Medical Xpress) -- Researchers at the University of California, Davis, have discovered a class of natural compounds found within the body that may someday lead to pain relief for millions of diabetics and others suffering ...

Diabetes created Jun 26, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

How does exercise affect nerve pain?

Exercise helps to alleviate pain related to nerve damage (neuropathic pain) by reducing levels of certain inflammation-promoting factors, suggests an experimental study in the June issue of Anesthesia & Analgesia, offici ...

Medical research created Jun 01, 2012 | popularity 5 / 5 (1) | comments 0

Chronic pain is relieved by cell transplantation in lab study (Update)

(Medical Xpress) -- Chronic pain, by definition, is difficult to manage, but a new study by UCSF scientists shows how a cell therapy might one day be used not only to quell some common types of persistent ...

Neuroscience created May 23, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study discovers unexpected source of diabetic neuropathy pain

Nearly half of all diabetics suffer from neuropathic pain, an intractable, agonizing and still mysterious companion of the disease. Now Yale researchers have identified an unexpected source of the pain and a potential target ...

Diabetes created May 15, 2012 | popularity 3.7 / 5 (3) | comments 0 | with audio podcast

New research finds powerful function of alpha 2 delta protein that controls neurotransmission

Scientists at Weill Cornell Medical College have discovered that the single protein -- alpha 2 delta -- exerts a spigot-like function, controlling the volume of neurotransmitters and other chemicals that flow between the ...

Medical research created May 13, 2012 | popularity 2.5 / 5 (2) | comments 0 | with audio podcast

A new drug to manage resistant chronic pain

Neuropathic pain, caused by nerve or tissue damage, is the culprit behind many cases of chronic pain. It can be the result of an accident or caused by a variety of medical conditions and diseases such as tumors, lupus, and ...

Neuroscience created Apr 30, 2012 | popularity 4 / 5 (3) | comments 0 | with audio podcast

New insight into pain mechanisms

(Medical Xpress) -- Researchers in the UCL Wolfson Institute for Biomedical Research have made a discovery which could help the development of analgesic drugs able to treat nerve damage-related pain.

Medical research created Apr 25, 2012 | popularity 5 / 5 (2) | comments 0

Scientists find anticonvulsant drug helps marijuana smokers kick the habit

Scientists at The Scripps Research Institute have found clinical evidence that the drug gabapentin, currently on the market to treat neuropathic pain and epilepsy, helps people to quit smoking marijuana (cannabis). Unlike ...

Addiction created Apr 24, 2012 | popularity not rated yet | comments 2 | with audio podcast


Neuropathic pain results from lesions or diseases affecting the somatosensory system. It may be associated with abnormal sensations called dysesthesia, which occur spontaneously and allodynia that occurs in response to external stimuli. Neuropathic pain may have continuous and/or episodic (paroxysmal) components. The latter are likened to an electric shock. Common qualities include burning or coldness, "pins and needles" sensations, numbness and itching. Nociceptive pain, by contrast, is more commonly described as aching.

Up to 7% to 8% of the European population is affected and in 5% of persons it may be severe. Neuropathic pain may result from disorders of the peripheral nervous system or the central nervous system (brain and spinal cord). Thus, neuropathic pain may be divided into peripheral neuropathic pain, central neuropathic pain, or mixed (peripheral and central) neuropathic pain.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Latest Spotlight News

Having both migraines, depression may mean smaller brain

(HealthDay)—Migraines and depression can each cause a great deal of suffering, but new research indicates the combination of the two may be linked to something else entirely—a smaller brain.

Brain can be trained in compassion, study shows

Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.

Slowing the aging process—only with antibiotics

Swiss scientists reveal the mechanism responsible for aging hidden deep within mitochondria—and dramatically slow it down in worms by administering antibiotics to the young.

Novel approach for influenza vaccination shows promise in early animal testing

A new approach for immunizing against influenza elicited a more potent immune response and broader protection than the currently licensed seasonal influenza vaccines when tested in mice and ferrets. The vaccine ...

Researchers complete largest genetic sequencing study of human disease

Researchers from Queen Mary, University of London have led the largest sequencing study of human disease to date, investigating the genetic basis of six autoimmune diseases.

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe ...

Research offers promising new approach to treatment of lung cancer

Researchers have developed a new drug delivery system that allows inhalation of chemotherapeutic drugs to help treat lung cancer, and in laboratory and animal tests it appears to reduce the systemic damage ...

Study details genes that control whether tumors adapt or die when faced with p53 activating drugs

When turned on, the gene p53 turns off cancer. However, when existing drugs boost p53, only a few tumors die – the rest resist the challenge. A study published in the journal Cell Reports shows how: tumors that live even i ...

Overeating learned in infancy, study suggests

In the long run, encouraging a baby to finish the last ounce in their bottle might be doing more harm than good.

Researchers analyse hunting behaviour of fish larvae in virtual reality

Moving objects attract greater attention – a fact exploited by video screens in public spaces and animated advertising banners on the Internet. For most animal species, moving objects also play a major ...