A team of scientists led by chemists Stephen Martin and James Sahn at The University of Texas at Austin have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway. The synthetic ...
Aug 16, 2017
2
1861
New research from King's College London has revealed a previously undiscovered mechanism of cellular communication, between neurons and immune cells, in neuropathic pain.
Nov 24, 2017
0
907
Sortilin, which is a protein expressed on the surface of nerve cells, plays a crucial role in pain development in laboratory mice—and in all likelihood in humans as well. This is the main conclusion of the study "Sortilin ...
Jun 20, 2019
2
14
(Medical Xpress)—Taxol, generically called paclitaxel, is a widely used drug in chemotherapy treatments. Taxol is used to treat cancer in the lungs, ovaries and breast, but it can also cause severe neuropathic pain and ...
Oct 30, 2013
0
0
There are three main types of pain: nociceptive pain, the type we're most familiar with, from bee stings and ankle strains to inflammatory arthritis. There's neuropathic pain, arising from damage to the peripheral nervous ...
Apr 9, 2020
0
121
A University of Toronto scientist has discovered the brain's frontal lobe is involved in pain transmission to the spine. If his findings in animals bear out in people, the discovery could lead to a new class of non-addictive ...
May 25, 2018
0
391
(HealthDay)—A small trial shows a dose-dependent reduction in peripheral neuropathic pain in patients with diabetes, according to a study published in the July issue of The Journal of Pain.
Jul 25, 2015
0
2004
Scientists at the University of California, Davis, have identified a key mechanism in neuropathic pain. The discovery could eventually benefit millions of patients with chronic pain from trauma, diabetes, shingles, multiple ...
Jul 7, 2015
0
5246
Pain is an important alarm system that alerts us to tissue damage and prompts us to withdraw from harmful situations. Pain is expected to subside as injuries heal, but many patients experience persistent pain long after recovery. ...
Aug 31, 2022
0
138
More than 20 million people in the U.S. suffer neuropathic pain. At least 25% of those cases are classified as unexplained and considered cryptogenic sensory polyneuropathy (CSPN). There is no information to guide a physician's ...
Oct 15, 2020
0
172
Neuropathic pain results from lesions or diseases affecting the somatosensory system. It may be associated with abnormal sensations called dysesthesia, which occur spontaneously and allodynia that occurs in response to external stimuli. Neuropathic pain may have continuous and/or episodic (paroxysmal) components. The latter are likened to an electric shock. Common qualities include burning or coldness, "pins and needles" sensations, numbness and itching. Nociceptive pain, by contrast, is more commonly described as aching.
Up to 7% to 8% of the European population is affected and in 5% of persons it may be severe. Neuropathic pain may result from disorders of the peripheral nervous system or the central nervous system (brain and spinal cord). Thus, neuropathic pain may be divided into peripheral neuropathic pain, central neuropathic pain, or mixed (peripheral and central) neuropathic pain.
This text uses material from Wikipedia licensed under CC BY-SA
