Nonalcoholic Steatohepatitis

Elevated cadmium levels linked to disease

People with higher levels of cadmium in their urine—evidence of chronic exposure to the heavy metal found in industrial emissions and tobacco smoke—appear to be nearly 3.5 times more likely to die of liver disease than ...

Surgery created May 09, 2013 | popularity not rated yet | comments 0

Sunshine hormone, vitamin D, may offer hope for treating liver fibrosis

Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases. In industrialized countries, the main causes of liver injury leading ...

Medical research created Apr 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Dietary medium chain triglycerides prevent nonalcoholic fatty liver disease

Scientists at the Arkansas Children's Nutrition Center, a U.S. Department of Agriculture Agricultural Research Service Human Nutrition Research Center at the University of Arkansas for Medical Sciences, led by Dr. Martin ...

Diseases, Conditions, Syndromes created Apr 24, 2013 | popularity 5 / 5 (1) | comments 0

Vitamin E identified as potential weapon against obesity

A potential new way to fight obesity-related illness has been uncovered, thanks to serendipitous research led by investigators at the Case Western Reserve University School of Medicine.

Overweight and Obesity created Apr 23, 2013 | popularity 5 / 5 (1) | comments 0

Some omega-3 oils better than others for protection against liver disease

(Medical Xpress)—Research at Oregon State University has found that one particular omega-3 fatty acid has a powerful effect in preventing liver inflammation and fibrosis – common problems that are steadily rising along ...

Diseases, Conditions, Syndromes created Feb 05, 2013 | popularity not rated yet | comments 0 | with audio podcast

Cardiovascular issues up mortality rates in patients with advanced fibrosis

New research reveals that advanced fibrosis is a significant predictor of mortality in patients with nonalcoholic fatty liver disease (NAFLD), largely brought about by cardiovascular causes. NAFLD alone was not associated ...

Diseases, Conditions, Syndromes created Apr 10, 2013 | popularity not rated yet | comments 0

Study identifies genetic variants linked to fatty liver disease in obese children

New research found the genetic variant Patatin-like phospholipase domain containing protein-3 (PNPLA3) acting in conjunction with the glucokinase regulatory protein (GCKR) is associated with increased susceptibility to fatty ...

Genetics created Mar 23, 2012 | popularity 5 / 5 (1) | comments 0

New animal model may lead to treatments for common liver disease

Scientists at Texas Biomed have developed the laboratory opossum as a new animal model to study the most common liver disease in the nation – afflicting up to 15 million Americans – and for which there is no cure.

Diseases, Conditions, Syndromes created Jul 03, 2012 | popularity not rated yet | comments 0

Researchers identify changes in cholesterol metabolic pathways

A new study from the Virginia Commonwealth University School of Medicine has identified molecular changes responsible for abnormal cholesterol production and metabolism in the livers of patients with a common liver condition, ...

Medical research created Jun 07, 2012 | popularity not rated yet | comments 0

Coffee consumption reduces fibrosis risk in those with fatty liver disease

Caffeine consumption has long been associated with decreased risk of liver disease and reduced fibrosis in patients with chronic liver disease. Now, newly published research confirms that coffee caffeine consumption reduces ...

Diseases, Conditions, Syndromes created Feb 02, 2012 | popularity 5 / 5 (1) | comments 0

High rates of disability and health care use for older Americans with cirrhosis

New research shows that older Americans with cirrhosis have significantly worse health status and greater functional disability compared to those without this potentially deadly disease. In fact, findings now published in ...

Diseases, Conditions, Syndromes created Jan 10, 2012 | popularity not rated yet | comments 0

NIH study to test treatment for fatty liver disease in children

With the launch of a new clinical trial supported by the National Institutes of Health, researchers are working to determine whether treating children diagnosed with the most severe form of fatty liver disease with a drug ...

Diseases, Conditions, Syndromes created Jan 12, 2012 | popularity not rated yet | comments 0

Modest alcohol consumption lowers risk and severity of liver disease

People with nonalcoholic fatty liver disease (NALFD) who consume alcohol in modest amounts – no more than one or two servings per day – are half as likely to develop hepatitis as non-drinkers with ...

Addiction created Apr 19, 2012 | popularity not rated yet | comments 0

Obesity and diabetes epidemics spur increase in nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) occurs when fat builds up in the liver. This accumulation of fat damages the liver and leads to cirrhosis. NASH is rapidly increasing in the U.S. mainly related to the epidemics of obesity ...

Diseases, Conditions, Syndromes created Dec 14, 2011 | popularity not rated yet | comments 0


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Non-alcoholic fatty liver disease (NAFLD) is one cause of a fatty liver, occurring when fat is deposited (steatosis) in the liver not due to excessive alcohol use. It is related to insulin resistance and the metabolic syndrome and may respond to treatments originally developed for other insulin-resistant states (e.g. diabetes mellitus type 2) such as weight loss, metformin and thiazolidinediones. Non-alcoholic steatohepatitis (NASH) is the most extreme form of NAFLD this being regarded as a major cause of cirrhosis of the liver of unknown cause.

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