Osteoarthritis

Twin research comes of age

Thanks to thousands of volunteer twins, scientists have discovered over 400 novel genes associated with over 30 diseases over the last two decades, marking a golden era in genetic discovery.

Jun 07, 2013
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How patient centered are medical decisions?

A national survey sample of adults who had discussions with their physicians in the preceding two years about common medical tests, medications and procedures often did not reflect a high level of shared decision making, ...

May 27, 2013
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Osteoarthritis (OA) also known as degenerative arthritis or degenerative joint disease or osteoarthrosis, is a group of mechanical abnormalities involving degradation of joints, including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion. A variety of causes—hereditary, developmental, metabolic, and mechanical—may initiate processes leading to loss of cartilage. When bone surfaces become less well protected by cartilage, bone may be exposed and damaged. As a result of decreased movement secondary to pain, regional muscles may atrophy, and ligaments may become more lax.

Treatment generally involves a combination of exercise, lifestyle modification, and analgesics. If pain becomes debilitating, joint replacement surgery may be used to improve the quality of life. OA is the most common form of arthritis, and the leading cause of chronic disability in the United States. It affects about 8 million people in the United Kingdom and nearly 27 million people in the United States.

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