Osteosarcoma

Cancers don't sleep: The Myc oncogene can disrupt circadian rhythm

The Myc oncogene can disrupt the 24-hour internal rhythm in cancer cells. Postdoctoral fellow Brian Altman, PhD, and graduate student Annie Hsieh, MD, both from the in the lab of Chi Van Dang, MD, PhD, director of the Abramson ...

Cancer created Apr 09, 2013 | popularity 3 / 5 (2) | comments 0 | with audio podcast

Two-drug combo more effective in treating sarcomas, study shows

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors. They report ...

Cancer created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

K9 osteosarcoma samples identify drivers of metastasis in pediatric bone cancer

Human osteosarcoma samples are hard to come by, making the disease difficult to study. However, K9 bone cancer is genetically indistinguishable from the human form of the disease, and over 10,000 canine patients develop the ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Discovering the secrets of tumor growth

Scientists at the University of Copenhagen's Center for Healthy Ageing have identified a compound that blocks the expression of a protein without which certain tumours cannot grow. This compound has the potential as an anticancer ...

Cancer created Jan 24, 2013 | popularity not rated yet | comments 0

Lexatumumab tolerated for pediatric solid tumors

(HealthDay)—Lexatumumab, an agonistic, full human monoclonal antibody against tumor necrosis factor-related apoptosis-inducing ligand receptor 2, is well tolerated and may lessen certain clinical symptoms ...

Cancer created Oct 16, 2012 | popularity 5 / 5 (1) | comments 0

Adult stem cells change their epigenome to generate new organs

A study developed by researchers at the IDIBELL, led by Manel Esteller, has identified epigenetic changes that occur in adult stem cells to generate different tissues of the human body.

Medical research created Oct 02, 2012 | popularity 5 / 5 (2) | comments 1

Novel surgery removes rare tumor, rebuilds face and jaw

Using a novel surgical approach, it's possible to rebuild a functional lower jaw and mouth, and preserve a patient's ability to eat and speak after removing an invasive facial tumor, according to a new report from Henry Ford ...

Surgery created Sep 07, 2012 | popularity not rated yet | comments 0

'Post-it note' on breast cancer gene signals risk of disease spreading

(Medical Xpress) -- A molecular 'post-it note' added to a breast cancer gene could flag up the risk that the disease will spread in patients, according to research published in the BJC today.

Cancer created Jul 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Biomarker predicts chemo response for osteosarcoma

(Medical Xpress) -- Scientists have found that a protein expressed by some cancers is a good predictor of how the cancer will respond to standard chemotherapy for osteosarcoma, the most common bone cancer in children. Knowing ...

Cancer created Jul 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Stopping the spread of a deadly childhood bone cancer

Many children with the bone cancer, osteosarcoma, die after the tumor spreads to their lungs. In a critical step toward finding a way to stop metastasis, researchers at Georgetown Lombardi Comprehensive Cancer Center say ...

Cancer created Apr 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Building bone from cartilage

A person has a tumor removed from her femur. A soldier is struck by an improvised explosive device and loses a portion of his tibia. A child undergoes chemotherapy for osteosarcoma but part of the bone dies as a result.

Medical research created Feb 14, 2012 | popularity 5 / 5 (1) | comments 0

New research could extend life of arthritic joints

A medication already approved to build bone mass in patients with osteoporosis also builds cartilage around joints and could potentially be repurposed to treat millions of people suffering from arthritis, according to orthopaedic ...

Medical research created Sep 21, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

With help from UCLA, teenage cancer patient begins to make strides

The doctors told Allie Newman that the pain in her right thigh was tendonitis, nothing to worry about. A little physical therapy and she'd be as good as new.

Cancer created Sep 14, 2011 | popularity 5 / 5 (2) | comments 0

Study shows bone fluoride levels not associated with osteosarcoma

The International and American Associations for Dental Research have released in its Journal of Dental Research a study that investigated bone fluoride levels in individuals with osteosarcoma, which is a rare, primary malign ...

Cancer created Jul 28, 2011 | popularity not rated yet | comments 0

Bone cancer, from the lab to the clinic

A new study into osteosarcoma - cancer of the bone - will use advances in genomic research and analysis to identify new genes that give rise to the condition and to create personalised blood tests for children and young adults ...

Cancer created Jun 08, 2011 | popularity not rated yet | comments 0


Osteosarcoma is an aggressive malignant neoplasm arising from primitive transformed cells of mesenchymal origin (and thus a sarcoma) that exhibit osteoblastic differentiation and produce malignant osteoid. It is the most common histological form of primary bone cancer.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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