Ovarian Cancer

Jolie's mastectomy spotlights legal battle over genes

Movie star Angelina Jolie tested positive for a "faulty gene" at the center of a high-profile legal battle in the United States that challenges whether human genes can belong to a corporation.

Cancer created May 16, 2013 | popularity not rated yet | comments 1

PARP inhibitor shows activity in pancreatic, prostate cancers among patients carrying BRCA mutations

In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced ...

Cancer created May 15, 2013 | popularity not rated yet | comments 0

What is BRCA1?

Actress Angelina Jolie has today written an op-ed in the New York Times explaining that she has opted to have a double mastectomy because she carries the hereditary BRCA1 gene, which she says increases her risk o ...

Cancer created May 15, 2013 | popularity 5 / 5 (1) | comments 2

Hysterectomy does not increase risk of cardiovascular disease

Having a hysterectomy with or without ovary removal in mid-life does not increase a woman's risk of cardiovascular disease compared to women who reach natural menopause, contrary to many previously reported studies, according ...

Cardiology created May 14, 2013 | popularity not rated yet | comments 0

Surgery can dramatically reduce genetic cancer risk

Women whose genes put them at a high risk of contracting breast cancer can dramatically reduce the danger by having a double mastectomy—but not eliminate it altogether, experts say.

Cancer created May 14, 2013 | popularity not rated yet | comments 0

Angelina Jolie says she had double mastectomy

Angelina Jolie says that she has had a preventive double mastectomy after learning she carried a gene that made it extremely likely she would get breast cancer.

Cancer created May 14, 2013 | popularity not rated yet | comments 0

Gene mutation as cause of breast and ovarian cancer

A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the ...

Cancer created May 10, 2013 | popularity not rated yet | comments 0

New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice

(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...

Cancer created May 08, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Wip1 could be new target for cancer treatment

Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...

Cancer created May 06, 2013 | popularity not rated yet | comments 0

New genetic clues to breast and ovarian cancer

(Medical Xpress)—A major international study involving a Simon Fraser University scientist has found that sequence differences in a gene crucial to the maintenance of our chromosomes' integrity predispose us to certain ...

Genetics created May 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

Genomics to reshape endometrial cancer treatment

The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.

Cancer created May 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

Computer algorithms help find cancer connections

Powerful data-sifting algorithms developed by computer scientists at Brown University are helping to untangle the profoundly complex genetics of cancer. In a study reported today in the New England Journal of Medicine, resear ...

Cancer created May 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

Team finds markers related to ovarian cancer survival and recurrence

(Medical Xpress)—Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with ...

Cancer created Apr 30, 2013 | popularity not rated yet | comments 1 | with audio podcast

Chemoresponse assay helps boost ovarian cancer survival

This spring, a team of researchers has released results from an eight-year study that shows improved survival rates for women diagnosed with ovarian cancer who undergo cancer tumor testing to determine the best treatment.

Cancer created Apr 25, 2013 | popularity 5 / 5 (1) | comments 0

Gene controls three different diseases

An international research consortium led by the Universitat Autònoma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending ...

Genetics created Apr 25, 2013 | popularity not rated yet | comments 0


Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early on and may include: bloating, pelvic pain, difficulty eating and frequent urination, and are easily confused with other illnesses.

Most (more than 90%) ovarian cancers are classified as "epithelial" and are believed to arise from the surface (epithelium) of the ovary. However, some evidence suggests that the fallopian tube could also be the source of some ovarian cancers. Since the ovaries and tubes are closely related to each other, it is thought that these fallopian cancer cells can mimic ovarian cancer. Other types may arise from the egg cells (germ cell tumor) or supporting cells. These cancers are grouped into the category of gynecologic cancer.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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