Ovarian Cancer

Thioridazine kills cancer stem cells in human while avoiding toxic side-effects of conventional cancer treatments

A team of scientists at McMaster University has discovered a drug, thioridazine, successfully kills cancer stem cells in the human while avoiding the toxic side-effects of conventional cancer treatments.

Cancer created May 24, 2012 | popularity 4.7 / 5 (55) | comments 5 | with audio podcast

New genetic clues to breast and ovarian cancer

(Medical Xpress)—A major international study involving a Simon Fraser University scientist has found that sequence differences in a gene crucial to the maintenance of our chromosomes' integrity predispose us to certain ...

Genetics created May 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

Computer algorithms help find cancer connections

Powerful data-sifting algorithms developed by computer scientists at Brown University are helping to untangle the profoundly complex genetics of cancer. In a study reported today in the New England Journal of Medicine, resear ...

Cancer created May 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

Linking of mutations in 12 genes to ovarian cancer may lead to more effective prevention

More patients with ovarian carcinoma carry cancer-predisposing mutations, and in more genes, than previously thought.

Cancer created Oct 25, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Team finds markers related to ovarian cancer survival and recurrence

(Medical Xpress)—Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with ...

Cancer created Apr 30, 2013 | popularity not rated yet | comments 1 | with audio podcast

You don't 'own' your own genes: Researchers raise alarm about loss of individual 'genomic liberty' due to gene patents

Humans don't "own" their own genes, the cellular chemicals that define who they are and what diseases they might be at risk for. Through more than 40,000 patents on DNA molecules, companies have essentially ...

Genetics created Mar 26, 2013 | popularity 4.8 / 5 (20) | comments 17 | with audio podcast

PARP inhibitors may have clinical utility in HER2-positive breast cancers

Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive ...

Cancer created Sep 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

Engineered T cells kill tumors but spare normal tissue in an animal model

The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal ...

Cancer created Apr 07, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Preclinical study identifies 'master' proto-oncogene that regulates ovarian cancer metastasis

Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins – known as Src – leads to ovarian cancer progression when exposed ...

Cancer created Jan 29, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Predicting the value of indexing symptoms for ovarian cancer

The use of symptom indices to identify patients with symptoms associated with ovarian cancer who may need further screening is increasing in both the UK and the US in an attempt to promote earlier diagnosis, but they may ...

Cancer created Jan 14, 2012 | popularity not rated yet | comments 0 | with audio podcast

Gene controls three different diseases

An international research consortium led by the Universitat Autònoma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending ...

Genetics created Apr 25, 2013 | popularity not rated yet | comments 0

Origin of aggressive ovarian cancer discovered

Cornell University researchers have discovered a likely origin of epithelial ovarian cancer (ovarian carcinoma), the fifth leading cause of cancer death among women in the United States.

Cancer created Mar 06, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Chemoresponse assay helps boost ovarian cancer survival

This spring, a team of researchers has released results from an eight-year study that shows improved survival rates for women diagnosed with ovarian cancer who undergo cancer tumor testing to determine the best treatment.

Cancer created Apr 25, 2013 | popularity 5 / 5 (1) | comments 0

Team finds biological indicator of aggressive, recurrent forms of prostate cancer

(Medical Xpress)—In a study to decipher clues about how prostate cancer cells grow and become more aggressive, Johns Hopkins urologists have found that reduction of a specific protein is correlated with the aggressiveness ...

Cancer created Aug 27, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Faulty proteins may prove significant in identifying new treatments for ovarian cancer

A constellation of defective proteins suspected in causing a malfunction in the body's ability to repair its own DNA could be the link scientists need to prove a new class of drugs will be effective in treating a broad range ...

Cancer created Jan 13, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast


Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early on and may include: bloating, pelvic pain, difficulty eating and frequent urination, and are easily confused with other illnesses.

Most (more than 90%) ovarian cancers are classified as "epithelial" and are believed to arise from the surface (epithelium) of the ovary. However, some evidence suggests that the fallopian tube could also be the source of some ovarian cancers. Since the ovaries and tubes are closely related to each other, it is thought that these fallopian cancer cells can mimic ovarian cancer. Other types may arise from the egg cells (germ cell tumor) or supporting cells. These cancers are grouped into the category of gynecologic cancer.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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