Ovarian Cancer

Thioridazine kills cancer stem cells in human while avoiding toxic side-effects of conventional cancer treatments

A team of scientists at McMaster University has discovered a drug, thioridazine, successfully kills cancer stem cells in the human while avoiding the toxic side-effects of conventional cancer treatments.

Cancer created May 24, 2012 | popularity 4.7 / 5 (55) | comments 5 | with audio podcast

You don't 'own' your own genes: Researchers raise alarm about loss of individual 'genomic liberty' due to gene patents

Humans don't "own" their own genes, the cellular chemicals that define who they are and what diseases they might be at risk for. Through more than 40,000 patents on DNA molecules, companies have essentially ...

Genetics created Mar 26, 2013 | popularity 4.8 / 5 (20) | comments 17 | with audio podcast

New nanoparticles that shut off cancer genes shrink tumors in mice

By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly ...

Cancer created Aug 15, 2012 | popularity 5 / 5 (7) | comments 2 | with audio podcast

Engineered T cells kill tumors but spare normal tissue in an animal model

The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal ...

Cancer created Apr 07, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice

(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...

Cancer created May 08, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Team finds mechanism of one of the most powerful tumor-suppressor proteins, Chd5

A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.

Cancer created Jan 10, 2013 | popularity 4.5 / 5 (6) | comments 0 | with audio podcast

Are human genes patentable?

(Medical Xpress)—On April 15, the Supreme Court will hear oral argument in Association for Molecular Pathology v. Myriad Genetics, a case that could answer the question, "Under what conditions, if any, ...

Genetics created Apr 11, 2013 | popularity 4.3 / 5 (6) | comments 16 | with audio podcast

DNA-repairing protein may be key to preventing recurrence of some cancers

Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...

Cancer created Jan 28, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists find new gene markers for cancer risk

A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian ...

Genetics created Mar 27, 2013 | popularity 5 / 5 (4) | comments 1

New tumor suppressor gene identified

A recent study published in Clinical Cancer Research suggests that the protein hVps37A suppresses tumor growth in ovarian cancer. The work, which was funded by the Austrian Science Fund FWF, shows, for th ...

Cancer created Feb 13, 2012 | popularity 4.8 / 5 (4) | comments 0

Avastin disappoints against ovarian cancer

Avastin, the blockbuster drug that just lost approval for treating breast cancer, now looks disappointing against ovarian cancer, too. Two studies found it did not improve survival for most of these patients and kept their ...

Cancer created Dec 28, 2011 | popularity 4.3 / 5 (4) | comments 1

High court throws out human gene patents

(AP) -- The Supreme Court on Monday threw out a lower court ruling allowing human genes to be patented, a topic of enormous interest to cancer researchers, patients and drug makers.

Genetics created Mar 26, 2012 | popularity 5 / 5 (3) | comments 1

DNA repair pathway score for predicting chemotherapy response in ovarian cancer patients

A DNA repair pathway-focused score has the potential to help determine if first-line platinum based chemotherapy can benefit advanced-stage ovarian cancer patients, according to a study published April 13 in the Journal of ...

Cancer created Apr 13, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Using millions of years of cell evolution in the fight against cancer

As the medical community continues to make positive strides in personalized cancer therapy, scientists know some dead ends are unavoidable. Drugs that target specific genes in cancerous cells are effective, but not all proteins ...

Genetics created Aug 07, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases

A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study published January 31 in the Open Access journal PLOS Pa ...

Cancer created Jan 31, 2013 | popularity 5 / 5 (3) | comments 1


Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early on and may include: bloating, pelvic pain, difficulty eating and frequent urination, and are easily confused with other illnesses.

Most (more than 90%) ovarian cancers are classified as "epithelial" and are believed to arise from the surface (epithelium) of the ovary. However, some evidence suggests that the fallopian tube could also be the source of some ovarian cancers. Since the ovaries and tubes are closely related to each other, it is thought that these fallopian cancer cells can mimic ovarian cancer. Other types may arise from the egg cells (germ cell tumor) or supporting cells. These cancers are grouped into the category of gynecologic cancer.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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