Diseases, Conditions, Syndromes

Experimental blood test accurately spots fibromyalgia

For the first time, researchers have evidence that fibromyalgia can be reliably detected in blood samples—work they hope will pave the way for a simple, fast diagnosis.

Diseases, Conditions, Syndromes

Back pain: we're treating it all wrong

Imagine a medical condition that becomes worse the more it's treated – let's call it Malady X. Millions are spent on expensive therapies, on surgery, injections and pills, yet Malady X continues to strike down the young ...

Neuroscience

Scientists discover powerful potential pain reliever

A team of scientists led by chemists Stephen Martin and James Sahn at The University of Texas at Austin have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway. The synthetic ...

Neuroscience

New mechanism of pain control revealed

Researchers in Japan have revealed a previously unknown mechanism for pain control involving a newly identified group of cells in the spinal cord, offering a potential target for enhancing the therapeutic effect of drugs ...

Neuroscience

Does an exploding brain network cause chronic pain?

A new study finds that patients with fibromyalgia have brain networks primed for rapid, global responses to minor changes. This abnormal hypersensitivity, called explosive synchronization (ES), can be seen in other network ...

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Pain is an unpleasant sensation often caused by intense or damaging stimuli such as stubbing a toe, burning a finger, putting alcohol on a cut, and bumping the "funny bone." The International Association for the Study of Pain has a definition that is widely used: "Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage".

Pain motivates the individual to withdraw from damaging situations, to protect a damaged body part while it heals, and to avoid similar experiences in the future. Most pain resolves promptly once the painful stimulus is removed and the body has healed, but sometimes pain persists despite removal of the stimulus and apparent healing of the body; and sometimes pain arises in the absence of any detectable stimulus, damage or disease.

Pain is the most common reason for physician consultation in the United States. It is a major symptom in many medical conditions, and can significantly interfere with a person's quality of life and general functioning. Psychological factors such as social support, hypnotic suggestion, excitement, or distraction can significantly modulate pain's intensity or unpleasantness.

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