Pancreatic Cancer

Molecular marker from pancreatic 'juices' helps identify pancreatic cancer

Researchers at Mayo Clinic have developed a promising method to distinguish between pancreatic cancer and chronic pancreatitis—two disorders that are difficult to tell apart. A molecular marker obtained from pancreatic ...

Cancer created May 20, 2013 | popularity not rated yet | comments 0

Breakthrough in how pancreatic cancer cells ingest nutrients points to new drug target

In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a ...

Cancer created May 13, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

PARP inhibitor shows activity in pancreatic, prostate cancers among patients carrying BRCA mutations

In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced ...

Cancer created May 15, 2013 | popularity not rated yet | comments 0

New nanoparticles that shut off cancer genes shrink tumors in mice

By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly ...

Cancer created Aug 15, 2012 | popularity 5 / 5 (7) | comments 2 | with audio podcast

Linking of mutations in 12 genes to ovarian cancer may lead to more effective prevention

More patients with ovarian carcinoma carry cancer-predisposing mutations, and in more genes, than previously thought.

Cancer created Oct 25, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Blocking 'scaffold' protein inhibits cancer growth, study finds

(Medical Xpress)—Researchers at the Stanford University School of Medicine have devised an entirely novel way to block biological signaling pathways that, when overactive, lead to many types of cancers. They've done so ...

Cancer created Apr 22, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Radioactive bacteria targets metastatic pancreatic cancer

Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them. The ex ...

Cancer created Apr 22, 2013 | popularity 5 / 5 (3) | comments 1 | with audio podcast

New vaccine attacks breast cancer in mice

Researchers from the University of Georgia and the Mayo Clinic in Arizona have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer ...

Cancer created Dec 12, 2011 | popularity 5 / 5 (10) | comments 2 | with audio podcast

New technology to tackle treatment-resistant cancers

Free-flowing cancer cells have been mapped with unprecedented accuracy in the bloodstream of patients with prostate, breast and pancreatic cancer, using a brand new approach, in an attempt to assess and control the disease ...

Cancer created Feb 03, 2012 | popularity 5 / 5 (5) | comments 2 | with audio podcast

One-two punch knocks out aggressive breast cancer cells

Doctors have long known that treating patients with multiple cancer drugs often produces better results than treatment with just a single drug. Now, a study from MIT shows that the order and timing of drug ...

Cancer created May 11, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Collagen-seeking synthetic protein could lead doctors to tumor locations

Johns Hopkins researchers have created a synthetic protein that, when activated by ultraviolet light, can guide doctors to places within the body where cancer, arthritis and other serious medical disorders ...

Medical research created Aug 29, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists find gene that inhibits pancreas cancer spread

Scientists have identified a gene that slows the spread of pancreatic cancer tumours, paving the way for targeted treatment of one of the deadliest forms of the disease, said a paper published Sunday.

Cancer created Apr 29, 2012 | popularity 5 / 5 (7) | comments 0

Early biomarker for pancreatic cancer identified

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently ...

Cancer created May 15, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Scientists find new molecule to target in pancreatic cancer treatment

Researchers at Mayo Clinic in Florida have identified a new target to improve treatment of pancreatic ductal adenocarcinoma cancer, which accounts for more than 95 percent of pancreatic cancer cases. This fast-growing, often ...

Cancer created Jan 03, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Gastroenterology special issue highlights the pancreas

The editors of Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute, are pleased to announce the publication of this year's highly anticipated special 13th issue. Published each M ...

Diseases, Conditions, Syndromes created May 08, 2013 | popularity not rated yet | comments 0


Pancreatic cancer refers to a malignant neoplasm originating from transformed cells arising in tissues forming the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors, is adenocarcinoma (tumors exhibiting glandular architecture on light microscopy) arising within the exocrine component of the pancreas. A minority arise from islet cells, and are classified as neuroendocrine tumors. The symptoms that lead to diagnosis depend on the location, the size, and the tissue type of the tumor. They may include abdominal pain and jaundice (if the tumor compresses the bile duct).

Pancreatic cancer is the fourth most common cause of cancer death across the globe. Pancreatic cancer often has a poor prognosis: for all stages combined, the 1- and 5-year relative survival rates are 25% and 6%, respectively; for local disease the 5-year survival is approximately 20% while the median survival for locally advanced and for metastatic disease, which collectively represent over 80% of individuals, is about 10 and 6 months respectively.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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