Pancreatic Ductal Adenocarcinoma
Early biomarker for pancreatic cancer identified
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently ...
Cancer
May 15, 2012 |
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Scientists find new molecule to target in pancreatic cancer treatment
Researchers at Mayo Clinic in Florida have identified a new target to improve treatment of pancreatic ductal adenocarcinoma cancer, which accounts for more than 95 percent of pancreatic cancer cases. This fast-growing, often ...
Cancer
Jan 03, 2013 |
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Gastroenterology special issue highlights the pancreas
The editors of Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute, are pleased to announce the publication of this year's highly anticipated special 13th issue. Published each M ...
Diseases, Conditions, Syndromes
May 08, 2013 |
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Study sheds light on how pancreatic cancer begins
A diagnosis of pancreatic cancer is particularly devastating since the prognosis for recovery is usually poor, with the cancer most often not detected until late stages.
Cancer
Nov 29, 2012 |
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Scientists create method to personalize chemotherapy drug selection
In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.
Cancer
Feb 14, 2013 |
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Mutated Kras spins a molecular loop that launches pancreatic cancer
Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lehal forms ...
Cancer
Jan 26, 2012 |
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Scientists break through pancreas cancer treatment barrier
Pancreas cancer tumors spread quickly and are notoriously resistant to treatment, making them among the deadliest of malignancies. Their resistance to chemotherapy stems in part from a unique biological barrier the tumor ...
Cancer
Mar 19, 2012 |
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Viruses kill pancreatic tumors in preclinical model
(Medical Xpress) -- An intra-tumor injection of a virus prevented further growth of some pancreatic tumors and eradicated others in mouse models of pancreatic ductal adenocarcinoma. However, some tumors continued growing ...
Medical research
Mar 20, 2012 |
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Aurora-A hinders tumor-suppressor to allow chemotherapy resistance
A protein abundantly found in treatment-resistant cancers holds an important tumor-suppressor out of the cell nucleus, where it would normally detect DNA damage and force defective cells to kill themselves, a team of scientists ...
Cancer
Feb 27, 2012 |
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Molecular master switch for pancreatic cancer identified, potential predictor of treatment outcome
A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation
Cancer
Feb 12, 2013 |
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Mutant Kras drives pancreatic cancer maintenance via metabolic pathways
A genetic mutation that drives the initiation of pancreatic cancer also manipulates metabolic pathways to support tumor growth and progression, scientists report in the journal Cell.
Cancer
Apr 26, 2012 |
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Receiving chemotherapy following removal of type of cancer near pancreas may improve survival
Patients who had surgery for periampullary cancer (a variety of types of cancer that are located in and near the head of the pancreas, including an area called the ampulla where the bile duct joins up with the pancreatic ...
Cancer
Jul 10, 2012 |
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Advanced pancreatic tumors depend on continued oncogene activity
Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.
Cancer
Apr 26, 2012 |
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Novel chemotherapy agent appears to be a promising pancreatic cancer treatment
A novel chemotherapeutic agent, the highly selective MEK1/2 inhibitor BAY 86-9766, may be a promising future treatment for pancreatic ductal adenocarcinoma (PDAC), according to preclinical results presented at the American ...
Cancer
Jun 20, 2012 |
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Blocking receptor in key hormone fires up enzyme to kill pancreatic cancer cells
Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme ...
Cancer
Aug 10, 2011 |
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