Restless Legs Syndrome

Restless legs syndrome, insomnia and brain chemistry: A tangled mystery solved?

Johns Hopkins researchers believe they may have discovered an explanation for the sleepless nights associated with restless legs syndrome (RLS), a symptom that persists even when the disruptive, overwhelming nocturnal urge ...

Neuroscience created May 07, 2013 | popularity 4.4 / 5 (5) | comments 1 | with audio podcast

Fruit flies with Restless Legs Syndrome point to a genetic cause

When flies are made to lose a gene with links to Restless Legs Syndrome (RLS), they suffer the same sleep disturbances and restlessness that human patients do. The findings reported online on May 31 in Current Biology strong ...

Genetics created May 31, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Insomnia may raise risk of heart attack, stroke

(HealthDay)—People with insomnia may have double the chances of a heart attack or stroke as opposed to those who sleep well, a study by Taiwanese researchers suggests.

Health created Nov 05, 2012 | popularity not rated yet | comments 0 | with audio podcast

Road map to mental illness is being redrawn, reshaping categories and research targets

When psychiatrists diagnose mental illness, they turn to an unwieldy book called the "Diagnostic and Statistical Manual of Mental Disorders," or DSM for short.

Psychology & Psychiatry created Oct 21, 2011 | popularity 5 / 5 (2) | comments 1

A new gene identified for restless legs syndrome

People suffering from restless legs syndrome (RLS) experience unpleasant sensations in the legs at night for which the only remedy is movement. Now, an international consortium from Europe, Canada and the US has identified ...

Genetics created Jul 14, 2011 | popularity not rated yet | comments 0 | with audio podcast

Information overload in drug side effect labeling

The lists of potential side effects that accompany prescription drugs have ballooned in size, averaging 70 reactions per drug, a number that can overwhelm physicians trying to select suitable treatments for their patients, ...

Medications created May 23, 2011 | popularity not rated yet | comments 0 | with audio podcast

Losing sleep? Scientists evaluate why

The issue of sleep deprivation has gone beyond the counting of sheep and into the scientific domain, as European researchers set up 'sleep labs' to study the biomedical and sociological factors keeping us ...

Health created May 03, 2013 | popularity 5 / 5 (3) | comments 0

Drugs may help relieve restless legs syndrome

(HealthDay)—People suffering from restless legs syndrome may find some relief by taking one of several drugs approved to treat the condition, a new review confirms.

Diseases, Conditions, Syndromes created Mar 04, 2013 | popularity not rated yet | comments 0

Court ruling may open door to more drug marketing

A decision by a federal appeals court this week could have a dramatic impact on the marketing of prescription drugs in America, potentially affecting patient care and everything from TV drug advertising to future government ...

Medications created Dec 06, 2012 | popularity not rated yet | comments 0

Nix the all-nighter: A good night's sleep is key to doing well on exams

As fall semesters wind down at the country's colleges and universities, students will be pulling all-night study sessions to prepare for final exams. Ironically, the loss of sleep during these all-nighters could actually ...

Health created Nov 26, 2012 | popularity 5 / 5 (1) | comments 0

Light from electronic screens at night linked to sleep loss

Like a lot of Americans, Amalie Drury has grown very attached to her smartphone.

Health created Jul 11, 2012 | popularity 5 / 5 (1) | comments 0

Study provides better terminology for diagnosing restless legs syndrome

(Medical Xpress) -- A study by Wits researchers has come to the aid of health practitioners who have previously had difficulty in diagnosing one of the most common neurological, but difficult to describe conditions, Restless ...

Diseases, Conditions, Syndromes created May 31, 2012 | popularity not rated yet | comments 0

Drug patch approved for advanced Parkinson's and restless leg syndrome

(HealthDay) -- The Neupro (rotigotine) transdermal system has been approved by the U.S. Food and Drug Administration to treat advanced Parkinson's disease and moderate-to-severe restless leg syndrome, the Belgian drug maker ...

Medications created Apr 03, 2012 | popularity not rated yet | comments 0

People with Parkinson's more likely to have leg restlessness than restless leg syndrome

People with Parkinson's disease may be more likely to have a movement disorder called leg motor restlessness, but not true restless legs syndrome as previous studies have suggested, according to a study published in the Nov. ...

Parkinson's & Movement disorders created Nov 09, 2011 | popularity not rated yet | comments 0

Restless legs syndrome may raise high blood pressure risk in middle-aged women

If you're a middle-aged woman with Restless Legs Syndrome, you may have a higher risk of developing high blood pressure, according to new research reported in Hypertension: Journal of the American Heart Association.

Cardiology created Oct 10, 2011 | popularity not rated yet | comments 0


Restless legs syndrome (RLS) or Willis-Ekbom disease is a neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can affect the arms, torso, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief.

RLS sensations can most closely be compared to an itching or tickling in the muscles, like "an itch you can't scratch" or an unpleasant "tickle that won't stop." The sensations typically begin or intensify during quiet wakefulness, such as when relaxing, reading, studying, or trying to sleep. In addition, most individuals with RLS have limb jerking during sleep, which is an objective physiologic marker of the disorder and is associated with sleep disruption. Some controversy surrounds the marketing of drug treatments for RLS. It is a "spectrum" disease with some people experiencing only a minor annoyance and others experiencing major disruption of sleep and significant impairments in quality of life.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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