Retinoblastoma is a rare pediatric cancer, with approximately 250–300 new cases per year in the United States and 8,000 worldwide. The cancer grows within the retina, a thin layer of cells at the back of the eye, and is ...
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Despite decades of medical advances, children who develop the pediatric eye cancer retinoblastoma often lose their vision or an eye due to a lack of specific, targeted therapies and a poor molecular understanding of the cancer. ...
Oct 3, 2022
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Childhood cancer rates have been rising slightly for the past few decades, and about 10,470 children in the U.S. under the age of 15 will be diagnosed with cancer in 2022, according to the American Cancer Society.
Sep 29, 2022
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Past research has shown that pesticide exposure increases the risk of cancer. Now, UCLA-led research has exposed which specific pesticides increase the risk of retinoblastoma—a rare eye tumor—in children.
Sep 13, 2022
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Scientists at St. Jude Children's Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in the RB1 gene. Retinoblastoma is a rare cancer of the retina, the thin tissue ...
Aug 5, 2021
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Retinoblastoma starts in the retina, the thin membrane at the back of the eye. Most patients are infants or toddlers when their cancer is found. Without treatment, the cancer spreads. Thanks to chemotherapy, surgery and other ...
May 6, 2021
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A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma. ...
Oct 12, 2020
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Retinoblastoma is a cancer that forms in the light-detecting cells in the back of the eye. It often appears in children under two years of age and can lead to blindness or eye removal. Most cancers are biopsied and studied ...
Nov 4, 2019
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An international team of researchers reports that modifying an adenovirus a certain way made it an effective tumor killer in mice with retinoblastoma. In their paper published in the journal Science Translational Medicine, ...
By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn't spread, Johns Hopkins Medicine researchers report new evidence that a domino effect in cells is responsible for the ...
Nov 12, 2018
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Retinoblastoma (Rb) is a rapidly developing cancer that develops in the cells of retina, the light-detecting tissue of the eye. In the developed world, Rb has one of the best cure rates of all childhood cancers (95-98%), with more than nine out of every ten sufferers surviving into adulthood.
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