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Immunology May 20, 2013 | 5 / 5 (5) | 0 |
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Medical research May 17, 2013 | 4.2 / 5 (5) | 0
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Cardiology May 16, 2013 | not rated yet | 0
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Arthritis & Rheumatism May 15, 2013 | not rated yet | 0
Today the BMJ calls for doctors and patients to join together as partners to improve healthcare.
Health May 14, 2013 | not rated yet | 0
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Inflammatory disorders May 14, 2013 | not rated yet | 0 |
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Immunology May 13, 2013 | 5 / 5 (1) | 0 |
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Arthritis & Rheumatism May 08, 2013 | 5 / 5 (5) | 0 |
Pfizer Inc.'s first-quarter net income rose 53 percent despite falling sales, mainly because the world's second-largest drugmaker took big charges a year ago. Pfizer's results fell short of Wall Street's ...
Other Apr 30, 2013 | not rated yet | 0
A gas associated with the smell of rotten eggs has proven to effectively reduce joint swelling, in research which could lead to advances in the treatment of arthritis.
Arthritis & Rheumatism Apr 29, 2013 | not rated yet | 0
Stems cells taken from just a few grams of body fat are a promising weapon against the crippling effects of osteoarthritis.
Arthritis & Rheumatism Apr 28, 2013 | not rated yet | 0
(Medical Xpress)—Scientists from the Manchester Collaborative Centre for Inflammation Research (MCCIR) have discovered why a particular cancer drug is so effective at killing cells. Their findings could ...
Cancer Apr 24, 2013 | 5 / 5 (2) | 0 |
(Medical Xpress)—Scientists studying the brain scans of chronic fatigue patients have found they use additional brain regions to do simple tasks requiring attention. This may explain the problems many sufferers ...
Diseases, Conditions, Syndromes Apr 23, 2013 | 5 / 5 (1) | 0
Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks flexible (synovial) joints. The process produces an inflammatory response of the capsule around the joints (synovium) secondary to swelling (hyperplasia) of synovial cells, excess synovial fluid, and the development of fibrous tissue (pannus) in the synovium. The pathology of the disease process often leads to the destruction of articular cartilage and ankylosis of the joints. Rheumatoid arthritis can also produce diffuse inflammation in the lungs, membrane around the heart (pericardium), the membranes of the lung (pleura), and white of the eye (sclera), and also nodular lesions, most common in subcutaneous tissue. Although the cause of rheumatoid arthritis is unknown, autoimmunity plays a pivotal role in both its chronicity and progression, and RA is considered a systemic autoimmune disease.
About 1% of the world's population is afflicted by rheumatoid arthritis, women three times more often than men. Onset is most frequent between the ages of 40 and 50, but people of any age can be affected. It can be a disabling and painful condition, which can lead to substantial loss of functioning and mobility if not adequately treated. It is a clinical diagnosis made on the basis of symptoms, physical exam, radiographs (X-rays) and labs, although the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) publish diagnostic guidelines. Diagnosis and long-term management are typically performed by a rheumatologist, an expert in joint, muscle and bone diseases.
Various treatments are available. Non-pharmacological treatment includes physical therapy, orthoses, occupational therapy and nutritional therapy but these do not stop the progression of joint destruction. Analgesia (painkillers) and anti-inflammatory drugs, including steroids, are used to suppress the symptoms, while disease-modifying antirheumatic drugs (DMARDs) are required to inhibit or halt the underlying immune process and prevent long-term damage. In recent times, the newer group of biologics has increased treatment options.
The name is based on the term "rheumatic fever", an illness which includes joint pain and is derived from the Greek word ῥεύμα-rheuma (nom.), ῥεύματος-rheumatos (gen.) ("flow, current"). The suffix -oid ("resembling") gives the translation as joint inflammation that resembles rheumatic fever. The first recognized description of rheumatoid arthritis was made in 1800 by Dr. Augustin Jacob Landré-Beauvais (1772–1840) of Paris.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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