Oncology & Cancer
Boosting sarcoma cell death
Ewing sarcomas – rare, aggressive childhood cancers – are derived from mesenchymal cells in bone and soft tissues, and children with metastatic disease have poor survival.
Oct 5, 2017
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Sarcoma
Oncology & Cancer
New drug overcomes resistance in patients with rare sarcoma
A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report ...
Nov 21, 2012
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Oncology & Cancer
Turning key metabolic process back on could make sarcoma more susceptible to treatment
Soft tissue sarcoma cells stop a key metabolic process which allows them to multiply and spread, and so restarting that process could leave these cancers vulnerable to a variety of treatments. The enzyme that controls the ...
Nov 26, 2019
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Oncology & Cancer
Researchers identify genes that cause rare hidden cancer
Several genes that cause sarcoma have been identified in the first comprehensive genetic map of sarcomas, generated by research led by Omico, the Garvan Institute of Medical Research and UNSW Sydney. The research has wide ...
Jan 19, 2023
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28
Oncology & Cancer
Common heart drug repurposed to treat rare cancer in Europe
A drug that's commonly used to treat high blood pressure is being repurposed for a rare tissue cancer in Europe. The medication, named propranolol, was recently granted Orphan Drug Designation by the European Commission (EC).
Jan 17, 2017
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Oncology & Cancer
Scientists develop potential new treatment for common soft-tissue childhood cancer
Scientists have developed a potential new therapeutic approach for synovial sarcoma, one of the most common soft-tissue cancers in teenagers and young adults. At present the long-term survival rates for synovial sarcoma patients ...
Nov 20, 2018
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Genetics
Two new genes linked to amyotrophic lateral sclerosis and related disorders
(Medical Xpress)—A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, ...
Mar 18, 2013
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Oncology & Cancer
A new route to blocking children's bone cancer
Ewing sarcoma is a bone cancer that appears mainly in teenagers. Due to a single defective gene, once it spreads to distant organs it is hard to treat. Researchers at the Weizmann Institute of Science have discovered molecular ...
Oct 2, 2019
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Oncology & Cancer
In Norway, risk of SCC after organ transplant has fallen
(HealthDay)—For organ recipients in Norway, the risk of skin cancer, particularly squamous cell carcinoma (SCC), has decreased since the mid-1980s, according to a study published online Oct. 18 in JAMA Dermatology.
Oct 20, 2017
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1
Oncology & Cancer
First extensive immune profile of sarcomas shows some likely susceptible to immunotherapy
Sarcomas—cancers of the connective tissues like muscles, joints, fat and bone—come in dozens of subtypes. Clinical trial results have been mixed when treating these diverse tumors with immunotherapy, a targeted therapeutic ...
May 2, 2017
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