Gamma-aminobutyric acid (GABA) deficits have been implicated in schizophrenia and depression. In schizophrenia, deficits have been particularly well-described for a subtype of GABA neuron, the parvalbumin fast-spiking interneurons. ...
Neuroscience Mar 13, 2013 | 5 / 5 (1) | 0
Many lines of evidence indicate that schizophrenia is a disorder of neurodevelopment. For example, genes implicated in the heritable risk for schizophrenia are also implicated in the development of nerve cells and their connections. ...
Psychology & Psychiatry Mar 06, 2013 | not rated yet | 0
The perpetration of homicide by people with mental disorders has received much attention, but their risk of being victims of homicide has rarely been examined. Yet such information may help develop more effective strategies ...
Psychology & Psychiatry Mar 05, 2013 | 5 / 5 (1) | 0
Researchers at Karolinska Institutet in Sweden have found an explanation for why the level of kynurenic acid (KYNA) is higher in the brains of people with schizophrenia or bipolar disease with psychosis. The study, which ...
Psychology & Psychiatry Mar 05, 2013 | 5 / 5 (1) | 0
Study reveals UK's declining health performance compared to other high income countries over past 20 years
Six decades of universal free health care, the introduction of widespread public health initiatives (e.g., tobacco control, cancer screening, and immunization), and substantial increases in health expenditure have failed ...
Health Mar 04, 2013 | not rated yet | 0
(Medical Xpress)—More than half of all patients suffering from schizophrenia do not take antipsychotic medication as prescribed, although this is essential for their effective treatment, according to research published ...
Psychology & Psychiatry Mar 04, 2013 | not rated yet | 0
Brain images from newborns are giving scientists a glimpse of the future - not just into the lives of their tiny subjects but also paths to treatment for adult patients with schizophrenia and Alzheimer's disease.
Neuroscience Feb 27, 2013 | not rated yet | 0
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Psychology & Psychiatry Feb 27, 2013 | not rated yet | 0
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Psychology & Psychiatry Feb 20, 2013 | not rated yet | 0
A study of eye movements in schizophrenia patients provides new evidence of impaired reading fluency in individuals with the mental illness.
Psychology & Psychiatry Feb 19, 2013 | 4 / 5 (1) | 1
Two years ago, researcher Josef Bless was listening to music on his phone when he suddenly had an idea.
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(Medical Xpress)—New research from King's College London's Institute of Psychiatry and Karolinska Institutet, Sweden, has found that adolescents whose verbal performance drops off are at increased risk ...
Psychology & Psychiatry Jan 22, 2013 | 5 / 5 (1) | 0
A new study from Lund University in Sweden shows that the average life expectancy of men and women with schizophrenia is 15 years and 12 years shorter respectively than for those who do not suffer from the disease. The study ...
Psychology & Psychiatry Jan 21, 2013 | 5 / 5 (2) | 0
Choline, an essential nutrient similar to the B vitamin and found in foods such as liver, muscle meats, fish, nuts and eggs, when given as a dietary supplement in the last two trimesters of pregnancy and in early infancy, ...
Psychology & Psychiatry Jan 15, 2013 | not rated yet | 0
Schizophrenia (/ˌskɪtsɵˈfrɛniə/ or /ˌskɪtsɵˈfriːniə/) is a mental disorder characterized by a breakdown of thought processes and by poor emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social or occupational dysfunction. The onset of symptoms typically occurs in young adulthood, with a global lifetime prevalence of about 0.3–0.7%. Diagnosis is based on observed behavior and the patient's reported experiences.
Genetics, early environment, neurobiology, and psychological and social processes appear to be important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Current research is focused on the role of neurobiology, although no single isolated organic cause has been found. The many possible combinations of symptoms have triggered debate about whether the diagnosis represents a single disorder or a number of discrete syndromes. Despite the etymology of the term from the Greek roots skhizein (σχίζειν, "to split") and phrēn, phren- (φρήν, φρεν-; "mind"), schizophrenia does not imply a "split mind" and it is not the same as dissociative identity disorder—also known as "multiple personality disorder" or "split personality"—a condition with which it is often confused in public perception.
The mainstay of treatment is antipsychotic medication, which primarily suppresses dopamine (and sometimes serotonin) receptor activity. Psychotherapy and vocational and social rehabilitation are also important in treatment. In more serious cases—where there is risk to self and others—involuntary hospitalization may be necessary, although hospital stays are now shorter and less frequent than they once were.
The disorder is thought mainly to affect cognition, but it also usually contributes to chronic problems with behavior and emotion. People with schizophrenia are likely to have additional (comorbid) conditions, including major depression and anxiety disorders; the lifetime occurrence of substance abuse is almost 50%. Social problems, such as long-term unemployment, poverty and homelessness, are common. The average life expectancy of people with the disorder is 12 to 15 years less than those without, the result of increased physical health problems and a higher suicide rate (about 5%).
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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