The classic symptoms of schizophrenia paranoia, hallucinations, the inability to function sociallycan be managed with antipsychotic drugs. But exactly how these drugs work has long been a mystery.
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Everyday tasks such as going to work or connecting with friends require us to have a certain level of motivation to carry out those actions, but people suffering from schizophrenia often lack this drive. Associate Professor ...
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Schizophrenia is a complex and chronic mental disorder affecting more than 2 million people in the United States.
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Schizophrenia is a chronic illness that most often comes on in late adolescence or young adulthood and can devastate patients lives. Many physicians and researchers believe that early intervention can increase the chances ...
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Understanding the actions of other people can be difficult for those with schizophrenia. Vanderbilt University researchers have discovered that impairments in a brain area involved in perception of social stimuli may be partly ...
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Faulty energy production in brain cells leads to disorders ranging from Parkinson's to intellectual disability
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When Chris Marciano was 4 years old, he would have a blistering tantrum whenever music came on the radio. By the second grade, his teacher described him as "not with us." At age 11, he was kicked out of school.
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Schizophrenia (/ˌskɪtsɵˈfrɛniə/ or /ˌskɪtsɵˈfriːniə/) is a mental disorder characterized by a breakdown of thought processes and by poor emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social or occupational dysfunction. The onset of symptoms typically occurs in young adulthood, with a global lifetime prevalence of about 0.3–0.7%. Diagnosis is based on observed behavior and the patient's reported experiences.
Genetics, early environment, neurobiology, and psychological and social processes appear to be important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Current research is focused on the role of neurobiology, although no single isolated organic cause has been found. The many possible combinations of symptoms have triggered debate about whether the diagnosis represents a single disorder or a number of discrete syndromes. Despite the etymology of the term from the Greek roots skhizein (σχίζειν, "to split") and phrēn, phren- (φρήν, φρεν-; "mind"), schizophrenia does not imply a "split mind" and it is not the same as dissociative identity disorder—also known as "multiple personality disorder" or "split personality"—a condition with which it is often confused in public perception.
The mainstay of treatment is antipsychotic medication, which primarily suppresses dopamine (and sometimes serotonin) receptor activity. Psychotherapy and vocational and social rehabilitation are also important in treatment. In more serious cases—where there is risk to self and others—involuntary hospitalization may be necessary, although hospital stays are now shorter and less frequent than they once were.
The disorder is thought mainly to affect cognition, but it also usually contributes to chronic problems with behavior and emotion. People with schizophrenia are likely to have additional (comorbid) conditions, including major depression and anxiety disorders; the lifetime occurrence of substance abuse is almost 50%. Social problems, such as long-term unemployment, poverty and homelessness, are common. The average life expectancy of people with the disorder is 12 to 15 years less than those without, the result of increased physical health problems and a higher suicide rate (about 5%).
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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