Sleeping Sickness

Awakening to new drugs against sleeping sickness

Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this ...

Cancer created May 17, 2013 | popularity 4 / 5 (1) | comments 1 | with audio podcast

Drug treatment corrects autism symptoms in mouse model

Autism results from abnormal cell communication. Testing a new theory, researchers at the University of California, San Diego School of Medicine have used a newly discovered function of an old drug to restore cell communications ...

Autism spectrum disorders created Mar 13, 2013 | popularity 5 / 5 (16) | comments 12 | with audio podcast

New tool in the fight against tropical diseases

A novel tool exploits baker's yeast to expedite the development of new drugs to fight multiple tropical diseases, including malaria, schistosomiasis, and African sleeping sickness. The unique screening method uses yeasts ...

Medical research created Feb 26, 2013 | popularity not rated yet | comments 0

US budget cuts could jeopardize development of life-saving tools against major killers

Across-the-board cuts to US R&D programs could have a devastating impact on efforts to develop new drugs for tuberculosis (TB) and HIV/AIDS, the world's first malaria vaccine, and other vital global health products in development, ...

Diseases, Conditions, Syndromes created Feb 26, 2013 | popularity not rated yet | comments 0

Tuberculosis and neglected diseases targeted by new center

A major new centre to boost the development of drugs to tackle the foremost diseases of the developing world is to be created at the University of Dundee.

Diseases, Conditions, Syndromes created Feb 13, 2013 | popularity not rated yet | comments 0

Sleeping sickness by stealth

(Medical Xpress)—Stealth is a well-known concept in military tactics. Almost since the invention of radar, the hunt began for counter-technologies to hide aircraft and missiles from detection – most successfully ...

Immunology created Feb 05, 2013 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Wild animals may contribute to the resurgence of African sleeping sickness

Wild animals may be a key contributor to the continuing spread of African sleeping sickness, new research published in PLOS Computational Biology shows. The West African form of the disease, also known as Gambiense Human ...

Diseases, Conditions, Syndromes created Jan 17, 2013 | popularity not rated yet | comments 0

Fighting sleep: Discovery may lead to new treatments for deadly sleeping sickness

While its common name may make it sound almost whimsical, sleeping sickness, or African trypanosomiasis, is in reality a potentially fatal parasitic infection that has ravaged populations in sub-Saharan Africa ...

Diseases, Conditions, Syndromes created Jan 17, 2013 | popularity 3.5 / 5 (2) | comments 1 | with audio podcast

New oral drug candidate for African sleeping sickness

A new oral-only treatment for sleeping sickness has entered Phase II/III clinical study in patients with late-stage sleeping sickness in the Democratic Republic of the Congo (DRC) and soon in Central African Republic (CAR). ...

Medications created Dec 06, 2012 | popularity not rated yet | comments 0

Open access initiative reveals drug hits for deadly neglected tropical diseases

The Drugs for Neglected Diseases initiative (DNDi) and Medicines for Malaria Venture (MMV) announce today the identification of three chemical series targeting the treatment of deadly neglected tropical diseases (NTDs), through ...

Diseases, Conditions, Syndromes created Nov 13, 2012 | popularity not rated yet | comments 0

Potential cure for Chagas disease

A Murdoch University international collaborative project has found a potential cure for the deadly Chagas disease.

Diseases, Conditions, Syndromes created Oct 25, 2012 | popularity 5 / 5 (1) | comments 0

Gene clue to drug resistance in African sleeping sickness

(Medical Xpress) -- Researchers have identified a gene that controls susceptibility to drug treatment in Trypanosoma brucei, the parasite responsible for African sleeping sickness.

Diseases, Conditions, Syndromes created Jun 19, 2012 | popularity 3 / 5 (2) | comments 0 | with audio podcast

Better tests for sleeping sickness

Lies Van Nieuwenhove, researcher at the Antwerp Institute of Tropical Medicine, has produced proteins imitating typical parts of the sleeping sickness parasite. They can be used in more efficient diagnostic ...

Diseases, Conditions, Syndromes created May 22, 2012 | popularity not rated yet | comments 0

Scientists take a step towards better sleeping sickness treatment

(Medical Xpress) -- Scientists at the University of Glasgow have taken a major step forward in the quest to develop new, safer drugs for the treatment of sleeping sickness.

Diseases, Conditions, Syndromes created Apr 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

Old drug shows new promise to treat leishmaniasis

(Medical Xpress) -- A study published yesterday shows that a drug called fexinidazole could potentially be used to treat visceral leishmaniasis, a parasitic disease that kills 50 000 to 60 000 people ...

Diseases, Conditions, Syndromes created Feb 02, 2012 | popularity not rated yet | comments 0 | with audio podcast


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