Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this ...
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Autism results from abnormal cell communication. Testing a new theory, researchers at the University of California, San Diego School of Medicine have used a newly discovered function of an old drug to restore cell communications ...
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A novel tool exploits baker's yeast to expedite the development of new drugs to fight multiple tropical diseases, including malaria, schistosomiasis, and African sleeping sickness. The unique screening method uses yeasts ...
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Across-the-board cuts to US R&D programs could have a devastating impact on efforts to develop new drugs for tuberculosis (TB) and HIV/AIDS, the world's first malaria vaccine, and other vital global health products in development, ...
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A major new centre to boost the development of drugs to tackle the foremost diseases of the developing world is to be created at the University of Dundee.
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(Medical Xpress)—Stealth is a well-known concept in military tactics. Almost since the invention of radar, the hunt began for counter-technologies to hide aircraft and missiles from detection – most successfully ...
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Wild animals may be a key contributor to the continuing spread of African sleeping sickness, new research published in PLOS Computational Biology shows. The West African form of the disease, also known as Gambiense Human ...
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While its common name may make it sound almost whimsical, sleeping sickness, or African trypanosomiasis, is in reality a potentially fatal parasitic infection that has ravaged populations in sub-Saharan Africa ...
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A new oral-only treatment for sleeping sickness has entered Phase II/III clinical study in patients with late-stage sleeping sickness in the Democratic Republic of the Congo (DRC) and soon in Central African Republic (CAR). ...
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The Drugs for Neglected Diseases initiative (DNDi) and Medicines for Malaria Venture (MMV) announce today the identification of three chemical series targeting the treatment of deadly neglected tropical diseases (NTDs), through ...
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A Murdoch University international collaborative project has found a potential cure for the deadly Chagas disease.
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(Medical Xpress) -- Researchers have identified a gene that controls susceptibility to drug treatment in Trypanosoma brucei, the parasite responsible for African sleeping sickness.
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Lies Van Nieuwenhove, researcher at the Antwerp Institute of Tropical Medicine, has produced proteins imitating typical parts of the sleeping sickness parasite. They can be used in more efficient diagnostic ...
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(Medical Xpress) -- Scientists at the University of Glasgow have taken a major step forward in the quest to develop new, safer drugs for the treatment of sleeping sickness.
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(Medical Xpress) -- A study published yesterday shows that a drug called fexinidazole could potentially be used to treat visceral leishmaniasis, a parasitic disease that kills 50 000 to 60 000 people ...
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Efficient signal transmission at sensory system synapses
(Medical Xpress)—Neurophysiologist like to think of neurons as communicating with spikes. If that were the whole story, it might be possible to imagine spike codes which could then be used to estimate the ...
A shot in the arm for old antibiotics: Silver boosts antibiotics
Slipping bacteria some silver could give old antibiotics new life, scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University reported June 19 in Science Translational Me ...
Fate of the heart: Researchers track cellular events leading to cardiac regeneration
In a study published in the June 19 online edition of the journal Nature, a scientific team led by researchers from the University of California, San Diego School of Medicine visually monitored the dynami ...
Scientists create way to see structures that store memories in living brain
Oscar Wilde called memory "the diary that we all carry about with us." Now a team of scientists has developed a way to see where and how that diary is written.
Mindfulness – a mental training that develops sustained attention that can change the ways people think, act and feel – could reduce symptoms of stress and depression and promote wellbeing among school children, according ...
Validating maps of the brain's resting state
Kick back and shut your eyes. Now stop thinking. You have just put your brain into what neuroscientists call its resting state. What the brain is doing when an individual is not focused on the outside world ...
New MERS virus spreads easily, deadlier than SARS, researchers show
A mysterious new respiratory virus that originated in the Middle East spreads easily between people and appears more deadly than SARS, doctors reported Wednesday after investigating the biggest outbreak in ...
Researchers explain how neural stem cells create new and varied neurons
A new study examining the brains of fruit flies reveals a novel stem cell mechanism that may help explain how neurons form in humans. A paper on the study by researchers at the University of Oregon appeared ...
Wireless subretinal prostheses allows blind mice to see light
(Medical Xpress)—A team of researchers from the U.S. and Scotland has developed a new type of retinal prostheses designed to restore sight to blind patients. In their paper published in the journal Nature Co ...
Brain can plan actions toward things the eye doesn't see
People can plan strategic movements to several different targets at the same time, even when they see far fewer targets than are actually present, according to a new study published in Psychological Science, a jour ...
