Pediatrics

First-ever in-utero surgery to treat spina bifida

A team of specialists at UPMC Magee-Womens Hospital and UPMC Children's Hospital of Pittsburgh have performed UPMC's first in-utero surgery to close an open neural tube defect in a baby months before her birth.

Genetics

Famous cancer-fighting gene also protects against birth defects

New research has revealed how the famous tumour suppressor gene p53 is surprisingly critical for development of the neural tube in female embryos. This is important because healthy development of the neural tube is needed ...

Oncology & Cancer

Study reveals safety signal from genes that mimic drugs

Prospective mothers taking a new class of cholesterol-lowering drugs might incur higher risk of spina bifida in their future children, according to a study published in the journal Drug Safety by researchers at Vanderbilt ...

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