Neuroscience

Leg exercise is critical to brain and nervous system health

Groundbreaking research shows that neurological health depends as much on signals sent by the body's large, leg muscles to the brain as it does on directives from the brain to the muscles. Published today in Frontiers in ...

Medical research

Scientists find key protein for spinal cord repair

A freshwater zebrafish costs less than two bucks at the pet store, but it can do something priceless: Its spinal cord can heal completely after being severed, a paralyzing and often fatal injury for humans.

Neuroscience

Paraplegic rats walk again after therapy, now we know why

With the help of robot-assisted rehabilitation and electrochemical spinal cord stimulation, rats with clinically relevant spinal cord injuries regained control of their otherwise paralyzed limbs. But how do brain commands ...

Neuroscience

Researchers rebuild the brain's circuitry

Neuron transplants have repaired brain circuitry and substantially normalized function in mice with a brain disorder, an advance indicating that key areas of the mammalian brain are more reparable than was widely believed.

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A spinal cord injury (SCI) refers to any injury to the spinal cord that is caused by trauma instead of disease. Depending on where the spinal cord and nerve roots are damaged, the symptoms can vary widely, from pain to paralysis to incontinence. Spinal cord injuries are described at various levels of "incomplete", which can vary from having no effect on the patient to a "complete" injury which means a total loss of function.

Treatment of spinal cord injuries starts with restraining the spine and controlling inflammation to prevent further damage. The actual treatment can vary widely depending on the location and extent of the injury. In many cases, spinal cord injuries require substantial physical therapy and rehabilitation, especially if the patient's injury interferes with activities of daily life.

Spinal cord injuries have many causes, but are typically associated with major trauma from motor vehicle accidents, falls, sports injuries, and violence. Research into treatments for spinal cord injuries includes controlled hypothermia and stem cells, though many treatments have not been studied thoroughly and very little new research has been implemented in standard care.

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