Squamous Cell Carcinoma

New study links tanning beds to non-melanoma skin cancer

Indoor tanning beds can cause non-melanoma skin cancer – and the risk is greater the earlier one starts tanning, according to a new analysis led by UCSF.

Cancer created Oct 02, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Studies show drug combinations effective for melanoma

Promising new data on drug combinations to treat metastatic melanoma are presented at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna.

Cancer created Sep 29, 2012 | popularity not rated yet | comments 0

Combination of targeted treatment drugs delays resistance in melanoma patients

Combined treatment with two drugs targeting different points in the same growth-factor pathway delayed the development of treatment resistance in patients with BRAF-positive metastatic malignant melanoma. The results of a ...

Cancer created Sep 29, 2012 | popularity not rated yet | comments 0

Study pinpoints epigenetic function of common cancer-causing protein—it's not what science thought

(Medical Xpress)—Squamous cell carcinoma (SCC) is diagnosed in about 700,000 people in the United States every year. Commonly contributing to SCC is a protein called DNp63a – it goes abnormally high and the ability of ...

Genetics created Sep 26, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Reseach reveals genomic similarities between breast cancer, ovarian cancers

One subtype of breast cancer shares many genetic features with high-grade serous ovarian cancer, a cancer that is very difficult to treat, according to researchers supported by the National Institutes of ...

Cancer created Sep 23, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Skin cancer incidence up after pancreas transplantation

(HealthDay)—Nonmelanoma skin cancers (NMSCs) commonly occur after pancreas transplantation (PT), particularly in those who have a history of skin cancer, according to a study published in the October issue ...

Cancer created Sep 21, 2012 | popularity not rated yet | comments 0

Rating HPV biomarkers in head, neck cancers: Combinations work better than viral DNA in tumors alone

Not all head and neck cancers are created equal. Those started by infection with the human papillomavirus are less often fatal than those with other causes, such as smoking. Detection of a reliable fingerprint for HPV could ...

Cancer created Sep 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study shows breath analysis could help diagnose pulmonary nodules

A pilot study, published in the October 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed that breath testing could be used to discriminate between benign ...

Cancer created Sep 16, 2012 | popularity not rated yet | comments 0

In lung cancer, smokers have 10 times more genetic damage than never-smokers

Lung cancer patients with a history of smoking have 10 times more genetic mutations in their tumors than those with the disease who have never smoked, according to a new study from Washington University School of Medicine ...

Cancer created Sep 13, 2012 | popularity 5 / 5 (2) | comments 0

Definition of lung squamous cell carcinoma genome opens doors to better, more targeted therapies

A new paper published online in Nature holds out hope that people with the second most common type of lung cancer may one day benefit from targeted therapies that have transformed treatments for other lung cancer patients.

Cancer created Sep 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study suggests patients should be screened before receiving vemurafenib

Different genetic mistakes driving skin cancer may affect how patients respond to the drug vemurafenib, providing grounds to screen people with melanoma skin cancer before treatment, a new study by Cancer Research UK scientists ...

Cancer created Aug 14, 2012 | popularity not rated yet | comments 0 | with audio podcast

High-risk HPV present in subset of penile carcinomas

(HealthDay) -- High-risk human papillomavirus (hrHPV) infection is found in a subset of penile squamous cell carcinomas (PSCCs) that may develop from undifferentiated penile intraepithelial neoplasia (PeIN), ...

Cancer created Aug 13, 2012 | popularity not rated yet | comments 0

Superficial X-ray viable for basal, squamous cell carcinoma

(HealthDay) -- Superficial X-ray therapy remains a viable treatment for primary basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in select patients, according to a study published online July 23 ...

Cancer created Aug 06, 2012 | popularity not rated yet | comments 0

People with darker skin still at risk for melanoma

(HealthDay) -- Skin cancer is more common among white people, but people with darker skin are also at risk, a dermatology expert cautions.

Cancer created Jul 26, 2012 | popularity 5 / 5 (2) | comments 0

Immunosuppressant switch cuts skin cancer post-transplant

(HealthDay) -- In kidney-transplant patients with at least one cutaneous squamous-cell carcinoma, switching immunosuppressants (from calcineurin inhibitors to sirolimus) is associated with increased skin cancer-free ...

Cancer created Jul 26, 2012 | popularity not rated yet | comments 0


Squamous cell carcinoma (SCC or SqCC) is a form of skin cancer. Skin cancers fall into two groups, melanoma and non-melanoma; squamous cell carcinoma is a non-melanoma cancer. It is one of the most common cancers in humans and other animals.

Squamous cells are a type of epithelium cell forming the outermost layers of the skin and some organs in the body. Squamous cell carcinoma usually occurs on the skin, especially portions commonly exposed to the Sun, the face, ears, neck, hands, or arm. The main symptom is a growing bump that may have a rough, scaly surface and flat reddish patches. It may also occur inside the body wherever squamous cells are found, including the esophagus, urinary bladder, prostate, lung, vagina, and cervix, among others.

Despite the common name, squamous cell carcinomas arising in different body sites can show tremendous differences in their presenting signs and symptoms, natural history, prognosis, and response to treatment.

Though the use of these terms has been decreasing in the literature, SqCC is still sometimes referred to as "epidermoid carcinoma" and "squamous cell epithelium". During its earliest stages, it is sometimes known as "Bowen's disease".

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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