Immunology
Impaired neutrophils in autoimmunity
Patients with autoimmune diseases such as systemic lupus erythematosus (SLE) have higher blood levels of the protein S100A9, but the source of this protein has not been identified.
Jan 28, 2022
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6
Systemic Lupus Erythematosus
Immunology
New, targeted therapy inhibits specific immune cells associated with lupus nephritis
Lupus (systemic lupus erythematosus), an autoimmune disease in which the body recognizes and attacks its own tissues, can affect many organs, including the kidneys. About fifty percent of patients diagnosed with lupus develop ...
Jan 11, 2022
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15
Arthritis & Rheumatism
CrAss viral content: When it's in your gut, it might be good for your health
Autoimmune diseases are conditions in which the immune system mistakenly attacks the body. Scientists know from previous research that the composition of the gut microbiome, the billions of microorganisms living in the human ...
Dec 22, 2021
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50
Obstetrics & gynaecology
Research reveals racial and ethnic disparities persist in pregnancy outcomes of patients with lupus
While investigators have known that maternal and fetal outcomes of pregnancy among women with systemic lupus erythematosus (SLE) have improved over time, it is unknown whether the improved outcomes are shared equally among ...
Nov 8, 2021
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Diseases, Conditions, Syndromes
Nearly one third of lupus patients in one study had low responses to COVID-19 vaccines
New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that nearly 30% of patients with lupus in a multi-ethnic and multi-racial study had a low response to the new ...
Nov 2, 2021
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4
Diseases, Conditions, Syndromes
Study finds racial gaps in renal complications persist for children with lupus
New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that while hospitalized children with juvenile lupus have fewer adverse kidney outcomes overall, significant ...
Nov 2, 2021
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3
Arthritis & Rheumatism
Study finds COVID-19 vaccine not associated with severe disease flare in patients with rheumatic diseases
New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the COVID-19 vaccine was not associated with severe disease flares in patients with rheumatic diseases. ...
Nov 1, 2021
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2
Diseases, Conditions, Syndromes
Belimumab promising in combination therapy for refractory lupus
For patients with systemic lupus erythematosus (SLE) refractory to conventional treatment, belimumab after rituximab significantly reduces serum immunoglobulin (Ig)G anti-double stranded DNA (dsDNA) levels and the risk for ...
Oct 26, 2021
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2
Diseases, Conditions, Syndromes
Managing inflammation through the endothelin system
Experts in the endothelin system are investigating how regulation of this system can serve to improve diseases of inflammation such as lupus. Endothelins are a class of peptides that play a role in regulating blood pressure. ...
Oct 4, 2021
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Immunology
Evaluation of lupus arthritis using frequency domain optical imaging
Systemic lupus erythematosus (SLE), commonly referred to as simply "lupus," is an autoimmune disorder where the body's immune system attacks healthy tissue. Lupus affects somewhere between 20 to 150 people per 100,000, with ...
Sep 30, 2021
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