New research findings published in the Journal of Leukocyte Biology, suggest that synovial CD4+ T cells that produce IL-21 contribute to joint inflammation by activating synovial fibroblasts in rheumatoid arthritis patients. ...
Mar 2, 2017
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Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.
Mar 15, 2023
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In the autoimmune disease systemic lupus erythematosus or SLE, the immune system produces antibodies against parts of the body itself. How cells that produce those antibodies escape the normal "checks and balances" has been ...
Oct 10, 2018
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Massachusetts General Hospital (MGH) investigators have identified an inflammatory molecule that appears to play an essential role in the autoimmune disorder systemic lupus erythematosus, commonly known as lupus. In their ...
Apr 6, 2015
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Recurrent bouts of systemic lupus erythematosus, marked by the body's immune system attack of its own tissues, closely tracked with measureable upticks in growth in the gut of a certain species of bacteria.
Jun 27, 2023
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Deborah Berry had visited numerous health-care professionals, but no one was able to accurately diagnose and treat the many lumps and cuts on the inside of her mouth. Berry, who suffers from systemic lupus erythematosus, ...
May 6, 2015
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The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus erythematosus, SLE, an inflammatory ...
Mar 9, 2023
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New research shows that more than half of women with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) have fewer children than desired. While patient choice has some influence on the smaller family size, findings ...
Feb 16, 2012
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(HealthDay)—For patients with systemic lupus erythematosus (SLE), vitamin D3 supplementation does not affect interferon (IFN) signature, according to a study published in the July issue of Arthritis & Rheumatology.
Jul 10, 2015
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Systemic lupus erythematosus (SLE) is an autoimmune disease that produces autoantibodies and subsequent immune reactions that can lead to a variety of symptoms, including inflammation of the kidneys, or nephritis. When researchers ...
Jul 14, 2015
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