Medical research

Malaria, toxoplasmosis: Toward new lines of research?

A study realized by teams from the Institut Pasteur, the Institut Cochin and the Wellcome Trust Centre for Molecular Parasitology of the University of Glasgow, could redefine part of the present lines of research toward a ...

Diseases, Conditions, Syndromes

Feline friends?

A report showing that 350,000 people in the UK become infected with the Toxoplasma parasite each year has raised new concerns about its risks and has prompted a rethink of the dangers posed by cats.

Diseases, Conditions, Syndromes

Brazil reports 5,909 microcephaly cases since October 2015

Brazil's Health Ministry says it's received reports of 5,909 cases of microcephaly since the Zika virus outbreak started in October. But only 641 of those have been confirmed so far.

Medical research

Brain parasite has potential to unlock neurobiology secrets

(Medical Xpress)—Dr. Anita Koshy sees a common and typically harmless brain parasite as a potential key to unlocking secrets of neurobiology that can be used to intervene in diseases such as Alzheimer's and multiple sclerosis.

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Toxoplasmosis is a parasitic disease caused by the protozoan Toxoplasma gondii. The parasite infects most genera of warm-blooded animals, including humans, but the primary host is the felid (cat) family. Animals are infected by eating infected meat, by ingestion of feces of a cat that has itself recently been infected, or by transmission from mother to fetus. Cats are the primary source of infection to human hosts, although contact with raw meat, especially pork, is a more significant source of human infections in some countries. Fecal contamination of hands is a significant risk factor.

Over half of the world's human population is estimated to carry a Toxoplasma infection. The Centers for Disease Control and Prevention notes that overall seroprevalence in the United States as determined with specimens collected by the National Health and Nutritional Examination Survey (NHANES) between 1999 and 2004 was found to be 10.8%, with seroprevalence among women of childbearing age (15 to 44 years) 11%.

During the first few weeks post-exposure, the infection typically causes a mild flu-like illness or no illness. Thereafter, the parasite rarely causes any symptoms in otherwise healthy adults. However, those with a weakened immune system, such as AIDS patients or pregnant women, may become seriously ill, and it can occasionally be fatal. The parasite can cause encephalitis (inflammation of the brain) and neurologic diseases, and can affect the heart, liver, inner ears, and eyes (chorioretinitis). Recent research has also linked toxoplasmosis with brain cancer, Attention Deficit Hyperactivity Disorder, Obsessive Compulsive Disorder, and Schizophrenia.

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