Trimethylaminuria

Trimethylaminuria (TMAU), also known as fish odor syndrome or fish malodor syndrome, is a rare metabolic disorder that causes a defect in the normal production of the enzyme Flavin containing monooxygenase 3 (FMO3). When FMO3 is not working correctly or if not enough enzyme is produced, the body loses the ability to properly break down trimethylamine (TMA) from precursor compounds in food digestion into trimethylamine oxide (TMAO) through a process called N-oxygenation. Trimethylamine then builds up and is released in the person's sweat, urine, and breath, giving off a strong fishy odor or strong body odor. The odor is not necessarily fishy, and the type of odor can vary from time to time. In that sense, the alternate names referring solely to a fishy odor are misnomers.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

She's not interested in sex but he thinks she is

Imagine the following scenario: a woman and a man are having a conversation. She is interested in the conversation, and is friendly, smiling and warm. He interprets her behavior as sexual interest.

Scientists find Ebola virus is mutating

(Medical Xpress)—Researchers working at Institut Pasteur in France have found that the Ebola virus is mutating "a lot" causing concern in the African countries where the virus has killed over eight thous ...

A challenge to expedite Genervon's new ASL drug

(Medical Xpress)—The Ice Bucket Challenge to raise awareness for Amyotrophic lateral sclerosis (ALS) went viral on social media last summer. Over 1.2 million videos were posted on Facebook alone. The difficulty ...