Among patients with suspected stage I/II pulmonary sarcoidosis who were undergoing confirmation of the condition via tissue sampling, the use of the procedure known as endosonographic nodal aspiration compared with bronchoscopic ...
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(Medical Xpress)—Researchers at Colorado State University are launching the most realistic study ever conducted into how transmission of the tuberculosis pathogen triggers infectious disease, an investigation expected to ...
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An international team led by scientists at The Scripps Research Institute (TSRI), the Howard Hughes Medical Institute and Albert Einstein College of Medicine of Yeshiva University has identified a highly promising new anti-tuberculosis ...
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Secretary of State John Kerry on Tuesday hailed the 10th anniversary of a US program to battle AIDS, saying it has helped one million babies be born disease-free to mothers infected with HIV.
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A mosquito-borne disease that preys on the young and malnourished is sweeping across poverty-riven northern India again this monsoon season, with officials worried it could be the deadliest outbreak in nearly ...
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Tuberculosis, MTB, or TB (short for tubercle bacillus) is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body. It is spread through the air when people who have an active MTB infection cough, sneeze, or otherwise transmit their saliva through the air. Most infections in humans result in an asymptomatic, latent infection, and about one in ten latent infections eventually progress to active disease, which, if left untreated, kills more than 50% of those infected.
The classic symptoms are a chronic cough with blood-tinged sputum, fever, night sweats, and weight loss (the last giving rise to the formerly prevalent colloquial term "consumption"). Infection of other organs causes a wide range of symptoms. Diagnosis relies on radiology (commonly chest X-rays), a tuberculin skin test, blood tests, as well as microscopic examination and microbiological culture of bodily fluids. Treatment is difficult and requires long courses of multiple antibiotics. Social contacts are also screened and treated if necessary. Antibiotic resistance is a growing problem in (extensively) multi-drug-resistant tuberculosis. Prevention relies on screening programs and vaccination, usually with Bacillus Calmette-Guérin vaccine.
One third of the world's population is thought to have been infected with M. tuberculosis, and new infections occur at a rate of about one per second. In 2007 there were an estimated 13.7 million chronic active cases, and in 2010 8.8 million new cases, and 1.45 million deaths, mostly in developing countries. The absolute number of tuberculosis cases has been decreasing since 2006 and new cases since 2002. In addition, more people in the developing world contract tuberculosis because their immune systems are more likely to be compromised due to higher rates of AIDS. The distribution of tuberculosis is not uniform across the globe; about 80% of the population in many Asian and African countries test positive in tuberculin tests, while only 5–10% of the U.S. population test positive.
This text uses material from Wikipedia licensed under CC BY-SA
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