Type 1 Diabetes

Snapshot turns T cell immunology on its head

Challenging a universally accepted, longstanding consensus in the field of immunity requires hard evidence. New research from the Australian Research Council Centre of excellence in advanced Molecular imaging has shown the ...

Oct 06, 2015
popularity179 comments 1

Researchers dig for cause of dog diabetes

(HealthDay)—Like many other animals, man's best friend isn't immune to developing diabetes. But new research suggests that while the disease in dogs looks similar to type 1 diabetes in people, there are some significant ...

Sep 17, 2015
popularity66 comments 2

Morbidly obese toddler had adult diabetes: report

A three-year-old who tipped the scales at 35 kilograms (77 pounds) has become one of the youngest people ever diagnosed with a lifestyle-related form of diabetes that strikes adults, her doctor said Thursday.

Sep 17, 2015
popularity27 comments 1

Diabetes mellitus type 1 (Type 1 diabetes, T1DM, IDDM, or, formerly, juvenile diabetes) is a form of diabetes mellitus that results from autoimmune destruction of insulin-producing beta cells of the pancreas. The subsequent lack of insulin leads to increased blood and urine glucose. The classical symptoms are polyuria (frequent urination), polydipsia (increased thirst), polyphagia (increased hunger), and weight loss.

Incidence varies from 8-17/100,000 in Northern Europe and the U.S., with a high of about 35/100,000 in Scandinavia, to a low of 1/100,000 in Japan and China.

Eventually, type 1 diabetes is fatal unless treated with insulin. Injection is the most common method of administering insulin; other methods are insulin pumps and inhaled insulin. Pancreatic transplants have been used. Pancreatic islet cell transplantation is experimental, though growing.

Most people who develop type 1 are otherwise healthy. Although the cause of type 1 diabetes is still not fully understood, it is believed to be of immunological origin.

Type 1 can be distinguished from type 2 diabetes via a C-peptide assay, which measures endogenous insulin production.

Type 1 treatment must be continued indefinitely in all cases. Treatment is not intended to significantly impair normal activities, and can be done adequately if sufficient patient training, awareness, appropriate care, discipline in testing and dosing of insulin is taken. However, treatment remains quite burdensome for many people. Complications may be associated with both low blood sugar and high blood sugar, both largely due to the non-physiological manner in which insulin is replaced. Low blood sugar may lead to seizures or episodes of unconsciousness and requires emergency treatment. High blood sugar may lead to increased fatigue and can also result in long term damage to organs.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Researchers build a digital piece of brain

If you want to learn how something works, one strategy is to take it apart and put it back together again. For 10 years, a global initiative called the Blue Brain Project—hosted at the Ecole Polytechnique Federale de Lausanne ...

Compound doubles up on cancer detection

Tagging a pair of markers found almost exclusively on a common brain cancer yields a cancer signal that is both more obvious and more specific to cancer, according to a study published last week in the Proceedings of the ...

Women and men react differently to infidelity

If your partner has sex with someone else, it is considered infidelity - even if no emotions are involved. But it is also considered infidelity when your significant other develops a close personal relationship with someone ...