West Nile Virus

Deaths from West Nile virus hit record last year

U.S. health officials say last year was the worst ever for West Nile virus deaths.

Diseases, Conditions, Syndromes created May 13, 2013 | popularity not rated yet | comments 0

Mosquito survey identifies reservoir of disease

A large scale, five year study of mosquitoes from different ecological regions in Kenya, including savannah grassland, semi-arid Acacia thorn bushes, and mangrove swamps, found a reservoir of viruses carried by mosquitoes ...

Diseases, Conditions, Syndromes created May 09, 2013 | popularity 5 / 5 (1) | comments 0

Scientists have discovered how mosquitoes develop viral immunity

(Medical Xpress)—Published online in the prestigious Proceedings of the National Academy of Sciences (PNAS), the team from CSIRO's Australian Animal Health Laboratory, in Geelong, have shown Vago, a prote ...

Diseases, Conditions, Syndromes created Oct 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Peptide found to induce autophagy resulting in defense against diseases

(Medical Xpress)—A multi-disciplined team of researchers from the United States and The Netherlands has found that introducing a certain type of peptide into mice cells induces autophagy, which in turn helps in fighting ...

Medical research created Jan 31, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast report

Researchers identify unexpected bottleneck in the spread of herpes simplex virus

New research suggests that just one or two individual herpes virus particles attack a skin cell in the first stage of an outbreak, resulting in a bottleneck in which the infection may be vulnerable to medical ...

Medical research created Nov 05, 2012 | popularity 4.8 / 5 (6) | comments 1 | with audio podcast

Some brain cells are better virus fighters

(Medical Xpress)—Viruses often spread through the brain in patchwork patterns, infecting some cells but missing others. New research at Washington University School of Medicine in St. Louis helps explain ...

Medical research created Mar 07, 2013 | popularity 4 / 5 (2) | comments 0 | with audio podcast

Researchers identify Achilles heel of dengue virus, target for future vaccines

A team of scientists from the University of North Carolina at Chapel Hill and Vanderbilt University have pinpointed the region on dengue virus that is neutralized in people who overcome infection with the deadly pathogen. ...

Medical research created Apr 11, 2012 | popularity 5 / 5 (8) | comments 0 | with audio podcast

Emerging vector-borne diseases create new public health challenge

Human activities are advancing the spread of vector-borne, zoonotic diseases such as West Nile virus, Lyme disease and dengue fever, report scientists publishing a series of papers today in the journal The ...

Diseases, Conditions, Syndromes created Nov 30, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

West Nile virus transmission linked to land use patterns and 'super-spreaders'

After its initial appearance in New York in 1999, West Nile virus spread across the United States in just a few years and is now well established throughout North and South America. Both the mosquitoes that ...

Diseases, Conditions, Syndromes created Oct 20, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Infection warning system in cells contains targets for antiviral and vaccine strategies

Two new targets have been discovered for antiviral therapies and vaccines strategies that could enhance the body's defenses against such infectious diseases as West Nile and hepatitis C. The targets are within the infection ...

Immunology created Jul 30, 2012 | popularity not rated yet | comments 0 | with audio podcast

Building a better Rift Valley fever vaccine

University of Texas Medical Branch researchers have significantly improved an existing experimental vaccine for Rift Valley fever virus, making possible the development of a more effective defense against the dangerous mosquito-borne ...

Medical research created Jun 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

Hepatitis C treatment's side effects can now be studied in the lab

(Medical Xpress)—The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg ...

Diseases, Conditions, Syndromes created Nov 16, 2012 | popularity 4.5 / 5 (6) | comments 0 | with audio podcast

Plants provide accurate low-cost alternative for diagnosis of West Nile Virus

(Medical Xpress)—While the United States has largely been spared the scourge of mosquito-borne diseases endemic to the developing world—including yellow fever, malaria and dengue fever—mosquito-related ...

Diseases, Conditions, Syndromes created Oct 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study finds snakes in the wild harbor deadly mosquito-borne EEEV virus through hibernation

Snakes in the wild serve as hosts for the deadly mosquito-borne Eastern equine encephalomyelitis Virus (EEEV), possibly acting as a "bridge" to the next season, according to researchers studying endemic areas in the Tuskegee ...

Diseases, Conditions, Syndromes created Oct 01, 2012 | popularity not rated yet | comments 0

New approach needed to tackle emerging zoonotic diseases

(Medical Xpress)—A more coordinated approach to surveillance is required if emerging diseases which can spread from animals to humans are to be tackled, say scientists.

Diseases, Conditions, Syndromes created Sep 10, 2012 | popularity not rated yet | comments 0


West Nile virus (WNV) is a virus of the family Flaviviridae. Part of the Japanese encephalitis (JE) antigenic complex of viruses, it is found in both tropical and temperate regions. It mainly infects birds, but is known to infect humans, horses, dogs, cats, bats, chipmunks, skunks, squirrels, domestic rabbits, crows, robins, crocodiles and alligators. The main route of human infection is through the bite of an infected mosquito. Approximately 90% of West Nile Virus infections in humans are without any symptoms.

Image reconstructions and cryoelectron microscopy reveal a 45–50 nm virion covered with a relatively smooth protein surface. This structure is similar to the dengue fever virus; both belong to the genus Flavivirus within the family Flaviviridae. The genetic material of WNV is a positive-sense, single strand of RNA, which is between 11,000 and 12,000 nucleotides long; these genes encode seven non-structural proteins and three structural proteins. The RNA strand is held within a nucleocapsid formed from 12 kDa protein blocks; the capsid is contained within a host-derived membrane altered by two viral glycoproteins.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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