West Nile Virus
Some brain cells are better virus fighters
(Medical Xpress)—Viruses often spread through the brain in patchwork patterns, infecting some cells but missing others. New research at Washington University School of Medicine in St. Louis helps explain ...
Medical research
Mar 07, 2013 |
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Hepatitis C treatment's side effects can now be studied in the lab
(Medical Xpress)—The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg ...
Diseases, Conditions, Syndromes
Nov 16, 2012 |
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Researchers identify unexpected bottleneck in the spread of herpes simplex virus
New research suggests that just one or two individual herpes virus particles attack a skin cell in the first stage of an outbreak, resulting in a bottleneck in which the infection may be vulnerable to medical ...
Medical research
Nov 05, 2012 |
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Peptide found to induce autophagy resulting in defense against diseases
(Medical Xpress)—A multi-disciplined team of researchers from the United States and The Netherlands has found that introducing a certain type of peptide into mice cells induces autophagy, which in turn helps in fighting ...
Medical research
Jan 31, 2013 |
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Researchers see more West Nile virus in orchards and vineyards
Washington State University researchers have linked orchards and vineyards with a greater prevalence of West Nile virus in mosquitoes and the insects' ability to spread the virus to birds, horses and people.
Diseases, Conditions, Syndromes
Jan 30, 2013 |
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Candidate dengue vaccine shows promise in early-stage trial
A candidate dengue vaccine developed by scientists at the National Institutes of Health (NIH) has been found to be safe and to stimulate a strong immune response in most vaccine recipients, according to results from an early-stage ...
Diseases, Conditions, Syndromes
Jan 23, 2013 |
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Emerging vector-borne diseases create new public health challenge
Human activities are advancing the spread of vector-borne, zoonotic diseases such as West Nile virus, Lyme disease and dengue fever, report scientists publishing a series of papers today in the journal The ...
Diseases, Conditions, Syndromes
Nov 30, 2012 |
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Scientists testing improved early warning system for West Nile virus
(Medical Xpress)—When weather radar shows a funnel cloud, the tornado sirens howl, and folks run for cover. With outbreaks of West Nile virus, it's not that simple.
Diseases, Conditions, Syndromes
Nov 02, 2012 |
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Plants provide accurate low-cost alternative for diagnosis of West Nile Virus
(Medical Xpress)—While the United States has largely been spared the scourge of mosquito-borne diseases endemic to the developing world—including yellow fever, malaria and dengue fever—mosquito-related ...
Diseases, Conditions, Syndromes
Oct 24, 2012 |
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Scientists have discovered how mosquitoes develop viral immunity
(Medical Xpress)—Published online in the prestigious Proceedings of the National Academy of Sciences (PNAS), the team from CSIRO's Australian Animal Health Laboratory, in Geelong, have shown Vago, a prote ...
Diseases, Conditions, Syndromes
Oct 03, 2012 |
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Officials: West Nile outbreak 1 of largest in US
(AP) — There are four times the usual number of cases in the current West Nile outbreak in the U.S. and it's too early to say how bad it will be at year's end, federal health officials said.
Diseases, Conditions, Syndromes
Aug 22, 2012 |
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Researchers show long-term consequences of chronic virus infection
The cytomegalovirus (CMV) is a member of the herpesvirus family. Although most people carry CMV for life, it hardly ever makes them sick. Researchers from the Helmholtz Centre for Infection Research and from ...
Diseases, Conditions, Syndromes
Aug 16, 2012 |
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Infection warning system in cells contains targets for antiviral and vaccine strategies
Two new targets have been discovered for antiviral therapies and vaccines strategies that could enhance the body's defenses against such infectious diseases as West Nile and hepatitis C. The targets are within the infection ...
Immunology
Jul 30, 2012 |
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Building a better Rift Valley fever vaccine
University of Texas Medical Branch researchers have significantly improved an existing experimental vaccine for Rift Valley fever virus, making possible the development of a more effective defense against the dangerous mosquito-borne ...
Medical research
Jun 27, 2012 |
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Researchers develop new, safer method for making vaccines
While vaccines are perhaps medicine's most important success story, there is always room for improvement. Researchers at Oregon Health & Science University's Oregon National Primate Research Center (ONPRC) appear to have ...
Medical research
May 29, 2012 |
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West Nile virus (WNV) is a virus of the family Flaviviridae. Part of the Japanese encephalitis (JE) antigenic complex of viruses, it is found in both tropical and temperate regions. It mainly infects birds, but is known to infect humans, horses, dogs, cats, bats, chipmunks, skunks, squirrels, domestic rabbits, crows, robins, crocodiles and alligators. The main route of human infection is through the bite of an infected mosquito. Approximately 90% of West Nile Virus infections in humans are without any symptoms.
Image reconstructions and cryoelectron microscopy reveal a 45–50 nm virion covered with a relatively smooth protein surface. This structure is similar to the dengue fever virus; both belong to the genus Flavivirus within the family Flaviviridae. The genetic material of WNV is a positive-sense, single strand of RNA, which is between 11,000 and 12,000 nucleotides long; these genes encode seven non-structural proteins and three structural proteins. The RNA strand is held within a nucleocapsid formed from 12 kDa protein blocks; the capsid is contained within a host-derived membrane altered by two viral glycoproteins.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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