Newly discovered mechanism helps tumor cells evade the immune system early on
Tumors actively prevent the formation of immune responses by cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München ...
15 hours ago
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CAR T cell therapy targeting HER2 antigen shows promise against advanced sarcoma in clinical trial
Researchers at Texas Children's Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital and Houston Methodist have published results of a Phase I clinical trial of a ...
18 hours ago
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Unveiling immune features of heart failure paves the way for targeted therapies
In a recent study published in the Science Bulletin, researchers comprehensively examined the composition and phenotypic features of myeloid cells in human failing hearts at a single-cell level, offering valuable insights ...
10 hours ago
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Allergies can make you miserable. Here's how to track pollen levels near you
Allergy season can bring misery to tens of millions of Americans each year.
14 hours ago
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Researchers identify a cause of immunodeficiency after stroke and heart attack
Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack. These patients suffer immune disturbances and are very frequently susceptible to life-threatening bacterial infections. Until ...
Apr 23, 2024
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How B cells recognize new variants of SARS-CoV-2
B cells are part of the immune system's memory. Their memories of previous infections or vaccinations provide the template for antibodies that have a protective effect the next time they come into contact with a pathogen.
Apr 23, 2024
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Swimming short fibrous nasal drops achieve intraventricular administration
Adequate drug delivery across the blood-brain barrier is a critical factor in treating central nervous system (CNS) disorders. Inspired by swimming fish and the microstructure of the nasal cavity, Prof. Cui is the first to ...
Apr 23, 2024
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Bacteria in the intestine that change in response to inflammation could have an impact on our immune system
Gut bacteria have emerged as a focal point of scientific exploration, with their intricate roles in our metabolism, nutrition, and overall health coming into sharp focus. New research from the Technion—Israel Institute ...
Apr 22, 2024
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Improving cancer immunotherapy by prolonging T-cell survival
In the past decade, immunotherapy has emerged as the fourth pillar of cancer treatment, joining surgery, radiotherapy and chemotherapy. It is an approved treatment for 15 cancers, including melanoma and some types of lymphomas ...
Apr 22, 2024
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Hitchhiking of synthetic antigen stimulates antibody production against cancer cells
Researchers at the Indian Institute of Science (IISc) have designed a synthetic compound (antigen) that can latch on to a protein in blood and hitchhike a ride to the lymph node, where it can boost the production of antibodies ...
Apr 22, 2024
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Genetically engineering a treatment for incurable brain tumors
Purdue University researchers are developing and validating a patent-pending treatment for incurable glioblastoma brain tumors. Glioblastomas are almost always lethal with a median survival time of 14 months. Traditional ...
Apr 22, 2024
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Researchers identify connection between air pollutants and allergic diseases
A study by researchers at National Jewish Health published in the Annals of Allergy, Asthma & Immunology reports that air pollutants—including particulate matter, pollen, greenhouse gases, and other harmful substances—can ...
Apr 22, 2024
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Review highlights the potential and promise of CAR-T cell therapy in autoimmune diseases
Autoimmune disease (AID) refers to the condition in which the immune system identifies the body's own cells and tissues as foreign, resulting in systemic inflammation. The immune system's self-attack via autoreactive B and ...
Apr 22, 2024
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Researchers develop a new way to safely boost immune cells to fight cancer
Last year alone, more than 600,000 people in the United States died from cancer, according to the American Cancer Society. The relentless pursuit of understanding this complex disease has shaped medical progress in developing ...
Apr 19, 2024
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Signs of multiple sclerosis show up in blood years before symptoms, study finds
In a discovery that could hasten treatment for patients with multiple sclerosis (MS), UC San Francisco scientists have discovered a harbinger in the blood of some people who later went on to develop the disease.
Apr 19, 2024
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Engineered peptides open new avenue for immunotherapy drug development
In a new study published in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cancer Center have designed a new method for developing immunotherapy drugs using engineered peptides to elicit ...
Apr 19, 2024
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Study of cancer-induced liver inflammation finds a promising therapeutic target
Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy. Now, a team led by researchers ...
Apr 19, 2024
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A new therapeutic target for traumatic brain injury
For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, ...
Apr 19, 2024
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