Immunology

How COVID-19 triggers massive inflammation

A study led by researchers at Boston Children's Hospital explains for the first time why COVID-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage. Surprisingly, the ...

Medical research

New approach to treating arthritis and other inflammatory diseases

Researchers from Peter Mac have discovered an innovative way to dampen severe inflammation in mice, uncovering a potential new therapeutic approach for inflammatory and autoimmune conditions such as arthritis, psoriasis and ...

Arthritis & Rheumatism

Discovery of a potential new therapy for inflammatory arthritis

In a paper published today in the journal Science Translational Medicine, researchers at the Schroeder Arthritis Institute, part of University Health Network (UHN) in Toronto, have made a discovery that could lead to new ...

Immunology

Study finds unique form of chronic sinusitis in older patients

Older patients with a diagnosis of chronic sinusitis—a disease of the nasal cavity and paranasal sinuses that often persists over many years—have a unique inflammatory signature that may render them less responsive to ...

Diseases, Conditions, Syndromes

Study reveals a microbe's molecular role in Crohn's disease

Changes in the gut microbiome have long been linked with Crohn's disease and other forms of inflammatory bowel disease (IBD), but the biology behind those links has remained murky. Researchers at the Broad Institute, Massachusetts ...

Medical research

Chronic inflammation causes a reduction in NAD+

NAD+ (nicotinamide adenine dinucleotide), a key metabolite central to an efficient and healthy metabolism, declines with age. This previously unexplained phenomena is associated with numerous age-related diseases and has ...

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